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EIF5AL1 eukaryotic translation initiation factor 5A like 1 [ Homo sapiens (human) ]

Gene ID: 143244, updated on 2-Mar-2021

Summary

Official Symbol
EIF5AL1provided by HGNC
Official Full Name
eukaryotic translation initiation factor 5A like 1provided by HGNC
Primary source
HGNC:HGNC:17419
See related
Ensembl:ENSG00000253626
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EIF5A; eIF-4D; eIF-5A; EIF5AP1; eIF-5A1; eIF-5A-1; bA342M3.3
Orthologs
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Genomic context

See EIF5AL1 in Genome Data Viewer
Location:
10q22.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (79512533..79516440)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (81272289..81276196)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene tetrapeptide repeat homeobox 1 pseudogene 1 Neighboring gene uncharacterized LOC729815 Neighboring gene ribosomal protein S12 pseudogene 18 Neighboring gene surfactant protein A2

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ribosome binding IEA
Inferred from Electronic Annotation
more info
 
translation elongation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
mRNA transport IEA
Inferred from Electronic Annotation
more info
 
positive regulation of translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of translational termination IEA
Inferred from Electronic Annotation
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
translational elongation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear pore IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 5A-1-like
Names
Eukaryotic translation initiation factor 5A-1
Rev-binding factor
eukaryotic translation initiation factor 5A pseudogene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099692.2NP_001093162.1  eukaryotic translation initiation factor 5A-1-like

    See identical proteins and their annotated locations for NP_001093162.1

    Status: VALIDATED

    Source sequence(s)
    AL133481
    Consensus CDS
    CCDS53546.1
    UniProtKB/Swiss-Prot
    Q6IS14
    Related
    ENSP00000430706.2, ENST00000520547.3
    Conserved Domains (2) summary
    PLN03107
    Location:1150
    PLN03107; eukaryotic translation initiation factor 5A; Provisional
    cd04468
    Location:84152
    S1_eIF5A; S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    79512533..79516440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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