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Slc34a3 solute carrier family 34 (sodium phosphate), member 3 [ Mus musculus (house mouse) ]

Gene ID: 142681, updated on 16-Oct-2021

Summary

Official Symbol
Slc34a3provided by MGI
Official Full Name
solute carrier family 34 (sodium phosphate), member 3provided by MGI
Primary source
MGI:MGI:2159410
See related
Ensembl:ENSMUSG00000006469
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Npt2c; NptIIc; naPi-2c; AI649385; Npt2c-v1
Expression
Restricted expression toward kidney adult (RPKM 74.2) See more
Orthologs
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Genomic context

See Slc34a3 in Genome Data Viewer
Location:
2; 2 A3
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25118909..25124282, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25228897..25234270, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (25084417..25089727, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene sperm tail PG rich repeat containing 3 Neighboring gene family with sequence similarity 166, member A Neighboring gene tubulin, beta 4B class IVB Neighboring gene ring finger protein 224 Neighboring gene cysteine rich tail 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC159029

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables sodium:phosphate symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables sodium:phosphate symporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables sodium:phosphate symporter activity ISO
Inferred from Sequence Orthology
more info
 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular phosphate ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular phosphate ion homeostasis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phosphate ion transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in phosphate ion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in sodium ion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in sodium-dependent phosphate transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in sodium-dependent phosphate transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in brush border IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in brush border IDA
Inferred from Direct Assay
more info
PubMed 
located_in brush border membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
sodium-dependent phosphate transport protein 2C
Names
Na(+)-dependent phosphate cotransporter 2C
Na(+)/Pi cotransporter 2C
sodium-phosphate cotransporter IIC
sodium/phosphate cotransporter 2C
type IIc Na+/Pi-cotransporter
type IIc NaPi-cotransporter-v1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362748.1NP_001349677.1  sodium-dependent phosphate transport protein 2C isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AL732309
    Conserved Domains (1) summary
    TIGR01013
    Location:19505
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  2. NM_080854.3NP_543130.2  sodium-dependent phosphate transport protein 2C isoform 1

    See identical proteins and their annotated locations for NP_543130.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL732309, BC125326
    Consensus CDS
    CCDS15754.1
    UniProtKB/Swiss-Prot
    Q80SU6
    Related
    ENSMUSP00000006638.8, ENSMUST00000006638.8
    Conserved Domains (1) summary
    TIGR01013
    Location:79565
    2a58; Phosphate:Na+ Symporter (PNaS) Family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    25118909..25124282 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497681.3XP_006497744.1  sodium-dependent phosphate transport protein 2C isoform X5

    See identical proteins and their annotated locations for XP_006497744.1

    Conserved Domains (1) summary
    TIGR01013
    Location:19505
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  2. XM_006497683.3XP_006497746.1  sodium-dependent phosphate transport protein 2C isoform X5

    See identical proteins and their annotated locations for XP_006497746.1

    Conserved Domains (1) summary
    TIGR01013
    Location:19505
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  3. XM_006497679.2XP_006497742.1  sodium-dependent phosphate transport protein 2C isoform X3

    Conserved Domains (1) summary
    TIGR01013
    Location:72558
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  4. XM_006497677.2XP_006497740.1  sodium-dependent phosphate transport protein 2C isoform X2

    See identical proteins and their annotated locations for XP_006497740.1

    UniProtKB/Swiss-Prot
    Q80SU6
    Conserved Domains (1) summary
    TIGR01013
    Location:79565
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  5. XM_011239018.2XP_011237320.1  sodium-dependent phosphate transport protein 2C isoform X4

    Conserved Domains (1) summary
    TIGR01013
    Location:87543
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  6. XM_011239017.2XP_011237319.1  sodium-dependent phosphate transport protein 2C isoform X1

    Conserved Domains (1) summary
    TIGR01013
    Location:87573
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  7. XM_006497678.2XP_006497741.1  sodium-dependent phosphate transport protein 2C isoform X2

    See identical proteins and their annotated locations for XP_006497741.1

    UniProtKB/Swiss-Prot
    Q80SU6
    Conserved Domains (1) summary
    TIGR01013
    Location:79565
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  8. XM_017315536.2XP_017171025.1  sodium-dependent phosphate transport protein 2C isoform X1

    Conserved Domains (1) summary
    TIGR01013
    Location:87573
    2a58; Phosphate:Na+ Symporter (PNaS) Family
  9. XM_017315541.2XP_017171030.1  sodium-dependent phosphate transport protein 2C isoform X5

    Conserved Domains (1) summary
    TIGR01013
    Location:19505
    2a58; Phosphate:Na+ Symporter (PNaS) Family
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