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Fli1 Friend leukemia integration 1 [ Mus musculus (house mouse) ]

Gene ID: 14247, updated on 11-Jul-2021

Summary

Official Symbol
Fli1provided by MGI
Official Full Name
Friend leukemia integration 1provided by MGI
Primary source
MGI:MGI:95554
See related
Ensembl:ENSMUSG00000016087
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Si; EWS; Fli; SIC; Sic1; EWSR2; Fli-1; SIC-1
Expression
Broad expression in spleen adult (RPKM 10.2), thymus adult (RPKM 7.9) and 23 other tissues See more
Orthologs
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Genomic context

See Fli1 in Genome Data Viewer
Location:
9 A4; 9 17.74 cM
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (32333500..32454728, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (32422204..32543432, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (32229793..32348953, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39317 Neighboring gene predicted gene, 31755 Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 1 Neighboring gene predicted gene, 22060 Neighboring gene predicted gene, 31871 Neighboring gene predicted gene, 31928

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
Friend leukemia integration 1 transcription factor
Names
retroviral integration site protein Fli-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008026.5NP_032052.1  Friend leukemia integration 1 transcription factor

    See identical proteins and their annotated locations for NP_032052.1

    Status: VALIDATED

    Source sequence(s)
    AA183149, AC127581, AK036655, AK042111
    Consensus CDS
    CCDS40571.1
    UniProtKB/Swiss-Prot
    P26323
    UniProtKB/TrEMBL
    Q544B3, Q8BZ56
    Related
    ENSMUSP00000016231.7, ENSMUST00000016231.14
    Conserved Domains (2) summary
    cd08541
    Location:114204
    SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
    smart00413
    Location:280363
    ETS; erythroblast transformation specific domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    32333500..32454728 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510008.3XP_006510071.1  Friend leukemia integration 1 transcription factor isoform X2

    See identical proteins and their annotated locations for XP_006510071.1

    Conserved Domains (2) summary
    cd08541
    Location:81171
    SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
    smart00413
    Location:247330
    ETS; erythroblast transformation specific domain
  2. XM_006510009.4XP_006510072.1  Friend leukemia integration 1 transcription factor isoform X2

    See identical proteins and their annotated locations for XP_006510072.1

    Conserved Domains (2) summary
    cd08541
    Location:81171
    SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
    smart00413
    Location:247330
    ETS; erythroblast transformation specific domain
  3. XM_036154611.1XP_036010504.1  Friend leukemia integration 1 transcription factor isoform X1

    Conserved Domains (2) summary
    cd08541
    Location:114199
    SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
    smart00413
    Location:258341
    ETS; erythroblast transformation specific domain
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