U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SCP2D1 SCP2 sterol binding domain containing 1 [ Homo sapiens (human) ]

Gene ID: 140856, updated on 5-Aug-2022

Summary

Official Symbol
SCP2D1provided by HGNC
Official Full Name
SCP2 sterol binding domain containing 1provided by HGNC
Primary source
HGNC:HGNC:16211
See related
Ensembl:ENSG00000132631 AllianceGenome:HGNC:16211
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSD22; C20orf79; dJ1068E13.2
Summary
Predicted to enable sterol binding activity. Predicted to be involved in phospholipid transport; positive regulation of intracellular cholesterol transport; and steroid biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SCP2D1 in Genome Data Viewer
Location:
20p11.23
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (18813783..18814378)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (18865625..18866220)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (18794427..18795022)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 34 Neighboring gene long intergenic non-protein coding RNA 652 Neighboring gene SCP2D1 antisense RNA 1 Neighboring gene lysosome cell death regulator Neighboring gene uncharacterized LOC102724734 Neighboring gene uncharacterized LOC107985442 Neighboring gene uncharacterized LOC101929547

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC138229

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables sterol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in phospholipid transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of intracellular cholesterol transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in steroid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
SCP2 sterol-binding domain-containing protein 1
Names
sterol carrier protein 2-like protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178483.3NP_848578.1  SCP2 sterol-binding domain-containing protein 1

    See identical proteins and their annotated locations for NP_848578.1

    Status: VALIDATED

    Source sequence(s)
    AF418570
    Consensus CDS
    CCDS13139.1
    UniProtKB/Swiss-Prot
    Q548A4, Q9UJQ7
    Related
    ENSP00000366645.2, ENST00000377428.4
    Conserved Domains (1) summary
    pfam02036
    Location:60151
    SCP2; SCP-2 sterol transfer family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    18813783..18814378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    18865625..18866220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)