Format

Send to:

Choose Destination

ABHD16B abhydrolase domain containing 16B [ Homo sapiens (human) ]

Gene ID: 140701, updated on 22-Aug-2020

Summary

Official Symbol
ABHD16Bprovided by HGNC
Official Full Name
abhydrolase domain containing 16Bprovided by HGNC
Primary source
HGNC:HGNC:16128
See related
Ensembl:ENSG00000183260
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C20orf135; dJ591C20.1
Orthologs

Genomic context

See ABHD16B in Genome Data Viewer
Location:
20q13.33
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (63861498..63862988)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (62492566..62494341)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 46 Neighboring gene ZBTB46 antisense RNA 1 Neighboring gene chromosome 20 open reading frame 181 Neighboring gene uncharacterized LOC112268269 Neighboring gene TPD52 like 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member C5 Neighboring gene RNA, U1 small nuclear 134, pseudogene

Genomic regions, transcripts, and products

Phenotypes

Associated conditions

Description Tests
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
GeneReviews: Not available

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of abhydrolase domain containing 16B (ABHD16B) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC42974

Gene Ontology Provided by GOA

Function Evidence Code Pubs
acylglycerol lipase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
palmitoyl-(protein) hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phospholipase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
macromolecule depalmitoylation IEA
Inferred from Electronic Annotation
more info
 
monoacylglycerol catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylserine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein ABHD16B
Names
abhydrolase domain-containing protein 16B
alpha/beta hydrolase domain-containing protein 16B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080622.4NP_542189.1  protein ABHD16B

    See identical proteins and their annotated locations for NP_542189.1

    Status: VALIDATED

    Source sequence(s)
    AL118506
    Consensus CDS
    CCDS13539.1
    UniProtKB/Swiss-Prot
    Q9H3Z7
    Related
    ENSP00000358932.3, ENST00000369916.5
    Conserved Domains (1) summary
    pfam12695
    Location:194284
    Abhydrolase_5; Alpha/beta hydrolase family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    63861498..63862988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center