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per2 period circadian clock 2 [ Danio rerio (zebrafish) ]

Gene ID: 140633, updated on 26-Oct-2019

Summary

Official Symbol
per2provided by ZNC
Official Full Name
period circadian clock 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-011220-2
See related
Ensembl:ENSDARG00000034503
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
fj43b09; wu:fj43b09

Genomic context

See per2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
24
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (48309600..48375374, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (48455436..48521221, complement)
103 previous assembly Zv9 (GCF_000002035.4) 2 NC_007113.5 (48423772..48489568, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene lysophosphatidic acid receptor 5a Neighboring gene integral membrane protein 2Cb Neighboring gene hes family bHLH transcription factor 6 Neighboring gene uncharacterized LOC110437927 Neighboring gene C-type mannose receptor 2-like

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

  • Exercise-induced Circadian Regulation, organism-specific biosystem (from WikiPathways)
    Exercise-induced Circadian Regulation, organism-specific biosystem
    Exercise-induced Circadian Regulation
  • Herpes simplex infection, organism-specific biosystem (from KEGG)
    Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Herpes simplex infection, conserved biosystem (from KEGG)
    Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
transcription corepressor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
circadian regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
entrainment of circadian clock by photoperiod IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
entrainment of circadian clock by photoperiod IMP
Inferred from Mutant Phenotype
more info
PubMed 
locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
photoperiodism IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of circadian rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to UV IDA
Inferred from Direct Assay
more info
PubMed 
response to cold IDA
Inferred from Direct Assay
more info
PubMed 
response to hydrogen peroxide IEP
Inferred from Expression Pattern
more info
PubMed 
response to light stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to light stimulus IDA
Inferred from Direct Assay
more info
PubMed 
response to light stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
period circadian protein homolog 2
Names
per2a
zper2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_182857.2NP_878277.2  period circadian protein homolog 2

    See identical proteins and their annotated locations for NP_878277.2

    Status: VALIDATED

    Source sequence(s)
    BX890608, EH526771
    UniProtKB/TrEMBL
    F8W3K8
    Related
    ENSDARP00000088777.5, ENSDART00000098004.5
    Conserved Domains (3) summary
    cd00130
    Location:409499
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam12114
    Location:11891366
    Period_C; Period protein 2/3C-terminal region
    pfam14598
    Location:399499
    PAS_11; PAS domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    48309600..48375374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478637.1XP_021334312.1  period circadian protein homolog 2 isoform X2

    Conserved Domains (3) summary
    pfam12114
    Location:12071381
    Period_C; Period protein 2/3C-terminal region
    cl25986
    Location:399499
    PAS_3; PAS fold
    cl26464
    Location:8731110
    Atrophin-1; Atrophin-1 family
  2. XM_021478636.1XP_021334311.1  period circadian protein homolog 2 isoform X1

    Conserved Domains (3) summary
    pfam12114
    Location:12081382
    Period_C; Period protein 2/3C-terminal region
    cl25986
    Location:399499
    PAS_3; PAS fold
    cl26464
    Location:8801111
    Atrophin-1; Atrophin-1 family
  3. XM_009298837.3XP_009297112.1  period circadian protein homolog 2 isoform X3

    See identical proteins and their annotated locations for XP_009297112.1

    UniProtKB/TrEMBL
    F8W3K8
    Related
    ENSDARP00000124374.1, ENSDART00000148788.3
    Conserved Domains (3) summary
    cd00130
    Location:409499
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam12114
    Location:11891366
    Period_C; Period protein 2/3C-terminal region
    pfam14598
    Location:399499
    PAS_11; PAS domain
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