Format

Send to:

Choose Destination

ACTRT2 actin related protein T2 [ Homo sapiens (human) ]

Gene ID: 140625, updated on 25-Jan-2022

Summary

Official Symbol
ACTRT2provided by HGNC
Official Full Name
actin related protein T2provided by HGNC
Primary source
HGNC:HGNC:24026
See related
Ensembl:ENSG00000169717 MIM:608535; AllianceGenome:HGNC:24026
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARPM2; ARPT2; Arp-T2; HARPM2
Summary
The protein encoded by this intronless gene belongs to the actin family. Studies have shown that this protein may be involved in cytoskeletal organization similar to other cytoplasmic actin-related protein (ARP) subfamily members. Antibody raised against the human protein has been used to detect the protein by immunoblotting and immunofluorescence microscopy, demonstrating its specific synthesis in the testis, late in spermatid differentiation, and its localization in the calyx. [provided by RefSeq, Jul 2008]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ACTRT2 in Genome Data Viewer
Location:
1p36.32
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (3021467..3022903)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (2938031..2939467)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 34 Neighboring gene uncharacterized LOC105378598 Neighboring gene uncharacterized LOC107984904 Neighboring gene uncharacterized LOC105378599 Neighboring gene opioid growth factor receptor pseudogene Neighboring gene PRDM16 divergent transcript Neighboring gene PR/SET domain 16

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ25424

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
actin-related protein T2
Names
actin-related protein M2
actin-related protein hArpM2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080431.5NP_536356.3  actin-related protein T2

    See identical proteins and their annotated locations for NP_536356.3

    Status: REVIEWED

    Source sequence(s)
    AF440740, AK058153, AL356984, AW016204, BI825639, BP370015
    Consensus CDS
    CCDS45.1
    UniProtKB/Swiss-Prot
    Q8TDY3
    UniProtKB/TrEMBL
    Q96LK1
    Related
    ENSP00000367658.2, ENST00000378404.4
    Conserved Domains (2) summary
    smart00268
    Location:10377
    ACTIN; Actin
    cl17037
    Location:11377
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    3021467..3022903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center