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TCP10L t-complex 10 like [ Homo sapiens (human) ]

Gene ID: 140290, updated on 11-Jun-2021

Summary

Official Symbol
TCP10Lprovided by HGNC
Official Full Name
t-complex 10 likeprovided by HGNC
Primary source
HGNC:HGNC:11657
See related
Ensembl:ENSG00000242220 MIM:608365
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRED77; C21orf77; TCP10A-1; TCP10A-2; LINC00846
Expression
Restricted expression toward testis (RPKM 24.4) See more
Orthologs
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Genomic context

See TCP10L in Genome Data Viewer
Location:
21q22.11
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 21 NC_000021.9 (32573721..32585523, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (33946031..33957833, complement)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene eva-1 homolog C Neighboring gene exosome component 3 pseudogene 1 Neighboring gene CFAP298-TCP10L readthrough Neighboring gene RNA, 5S ribosomal pseudogene 490 Neighboring gene uncharacterized LOC105372782 Neighboring gene cilia and flagella associated protein 298

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough CFAP298-TCP10L

Readthrough gene: CFAP298-TCP10L, Included gene: CFAP298

Homology

Clone Names

  • FLJ10932, MGC34297

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor binding IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein self-association IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
T-complex protein 10A homolog 1
Names
T-complex protein 10A homolog 2
T-complex protein 10A-1
T-complex protein 10A-2
TCP10-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144659.7NP_653260.1  T-complex protein 10A homolog 1

    See identical proteins and their annotated locations for NP_653260.1

    Status: VALIDATED

    Source sequence(s)
    AF115967, AP000274, BC027970, BG721020, HY036551
    Consensus CDS
    CCDS13616.1
    UniProtKB/Swiss-Prot
    Q8TDR4
    Related
    ENSP00000300258.3, ENST00000300258.8

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p13 Primary Assembly

    Range
    32573721..32585523 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_018277.1: Suppressed sequence

    Description
    NM_018277.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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