Format

Send to:

Choose Destination

Evi5 ecotropic viral integration site 5 [ Mus musculus (house mouse) ]

Gene ID: 14020, updated on 25-Nov-2021

Summary

Official Symbol
Evi5provided by MGI
Official Full Name
ecotropic viral integration site 5provided by MGI
Primary source
MGI:MGI:104736
See related
Ensembl:ENSMUSG00000011831
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NB4S
Expression
Ubiquitous expression in frontal lobe adult (RPKM 3.7), placenta adult (RPKM 3.6) and 27 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Evi5 in Genome Data Viewer
Location:
5 F; 5 52.23 cM
Exon count:
28
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (107892661..108022973, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (107744795..107875107, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (108173814..108304126, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene -8.7 kb enhancer upstream of Gfi1 Neighboring gene predicted gene, 42147 Neighboring gene Gfi1 -35 kb enhancer Neighboring gene ubiquitin-conjugating enzyme E2D 2B Neighboring gene predicted gene, 42149 Neighboring gene small nucleolar RNA, C/D box 21 Neighboring gene predicted gene, 22270 Neighboring gene ribosomal protein L5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activator activity ISO
Inferred from Sequence Orthology
more info
 
enables small GTPase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in activation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde transport, endosome to Golgi ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ecotropic viral integration site 5 protein
Names
EVI-5

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001378824.1NP_001365753.1  ecotropic viral integration site 5 protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC138666
    Conserved Domains (2) summary
    smart00164
    Location:116324
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG1196
    Location:348693
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. NM_001378825.1NP_001365754.1  ecotropic viral integration site 5 protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC138666
    Conserved Domains (2) summary
    smart00164
    Location:116324
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    TIGR02168
    Location:361670
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  3. NM_007964.2NP_031990.2  ecotropic viral integration site 5 protein isoform 1

    See identical proteins and their annotated locations for NP_031990.2

    Status: VALIDATED

    Source sequence(s)
    AC117574, AC138666, AK134294, BI737814, CN456828, CV557033
    Consensus CDS
    CCDS39198.1
    UniProtKB/TrEMBL
    F8VPT6, Q3UYX4
    Related
    ENSMUSP00000108261.2, ENSMUST00000112642.8
    Conserved Domains (3) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    pfam06386
    Location:527674
    GvpL_GvpF; Gas vesicle synthesis protein GvpL/GvpF
    cl11555
    Location:456494
    DUF1129; Protein of unknown function (DUF1129)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    107892661..108022973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534781.3XP_006534844.1  ecotropic viral integration site 5 protein isoform X5

    Conserved Domains (2) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    TIGR02168
    Location:406709
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. XM_006534776.4XP_006534839.1  ecotropic viral integration site 5 protein isoform X1

    Conserved Domains (2) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG1196
    Location:392737
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_006534783.5XP_006534846.1  ecotropic viral integration site 5 protein isoform X6

    Conserved Domains (2) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG1196
    Location:392737
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. XM_006534780.5XP_006534843.1  ecotropic viral integration site 5 protein isoform X4

    Conserved Domains (2) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    TIGR02168
    Location:389714
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  5. XM_006534779.4XP_006534842.1  ecotropic viral integration site 5 protein isoform X3

    See identical proteins and their annotated locations for XP_006534842.1

    Conserved Domains (2) summary
    smart00164
    Location:116324
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG1196
    Location:348693
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  6. XM_011249407.4XP_011247709.1  ecotropic viral integration site 5 protein isoform X3

    See identical proteins and their annotated locations for XP_011247709.1

    Conserved Domains (2) summary
    smart00164
    Location:116324
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG1196
    Location:348693
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  7. XM_006534777.5XP_006534840.1  ecotropic viral integration site 5 protein isoform X2

    Conserved Domains (2) summary
    smart00164
    Location:144352
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG1196
    Location:376721
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  8. XM_030254127.2XP_030109987.1  ecotropic viral integration site 5 protein isoform X9

    Conserved Domains (2) summary
    smart00164
    Location:116324
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    TIGR02168
    Location:362658
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  9. XM_006534784.4XP_006534847.1  ecotropic viral integration site 5 protein isoform X7

    Conserved Domains (2) summary
    smart00164
    Location:71279
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG1196
    Location:303648
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  10. XM_006534785.5XP_006534848.1  ecotropic viral integration site 5 protein isoform X8

    Conserved Domains (2) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG1196
    Location:392737
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  11. XM_006534786.2XP_006534849.1  ecotropic viral integration site 5 protein isoform X10

    Related
    ENSMUSP00000114845.2, ENSMUST00000128723.8
    Conserved Domains (2) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    TIGR02168
    Location:389731
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  12. XM_011249408.4XP_011247710.1  ecotropic viral integration site 5 protein isoform X11

    Conserved Domains (2) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    TIGR02168
    Location:389731
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  13. XM_006534787.4XP_006534850.1  ecotropic viral integration site 5 protein isoform X12

    Related
    ENSMUSP00000119196.2, ENSMUST00000138111.8
    Conserved Domains (1) summary
    smart00164
    Location:160368
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
  14. XM_036164779.1XP_036020672.1  ecotropic viral integration site 5 protein isoform X13

    Related
    ENSMUSP00000121761.2, ENSMUST00000124034.8
    Conserved Domains (1) summary
    smart00164
    Location:116324
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
Support Center