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SPIN4 spindlin family member 4 [ Homo sapiens (human) ]

Gene ID: 139886, updated on 5-Aug-2022

Summary

Official Symbol
SPIN4provided by HGNC
Official Full Name
spindlin family member 4provided by HGNC
Primary source
HGNC:HGNC:27040
See related
Ensembl:ENSG00000186767 AllianceGenome:HGNC:27040
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TDRD28
Summary
Enables methylated histone binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be active in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See SPIN4 in Genome Data Viewer
Location:
Xq11.1
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (63347228..63351332, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (61772497..61776601, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (62567107..62571211, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene HERV-FRD provirus ancestral Env polyprotein pseudogene Neighboring gene SPIN4 antisense RNA 1 Neighboring gene chromobox 1 pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 1278 Neighboring gene Cdc42 guanine nucleotide exchange factor 9 Neighboring gene ARHGEF9 intronic transcript 1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ44984, MGC133224

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables methylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables methylated histone binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in gamete generation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012968.3NP_001012986.2  spindlin-4

    See identical proteins and their annotated locations for NP_001012986.2

    Status: VALIDATED

    Source sequence(s)
    AL158203
    Consensus CDS
    CCDS43964.1
    UniProtKB/Swiss-Prot
    Q56A73, Q5JUL2
    UniProtKB/TrEMBL
    X6R8Y7
    Related
    ENSP00000364018.3, ENST00000374884.3
    Conserved Domains (1) summary
    pfam02513
    Location:4189
    Spin-Ssty; Spin/Ssty Family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    63347228..63351332 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    61772497..61776601 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)