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ACTRT1 actin related protein T1 [ Homo sapiens (human) ]

Gene ID: 139741, updated on 12-Oct-2019

Summary

Official Symbol
ACTRT1provided by HGNC
Official Full Name
actin related protein T1provided by HGNC
Primary source
HGNC:HGNC:24027
See related
Ensembl:ENSG00000123165 MIM:300487
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AIP1; ARIP1; ARPT1; HSD27
Summary
This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010]
Orthologs

Genomic context

See ACTRT1 in Genome Data Viewer
Location:
Xq25
Exon count:
1
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (128050962..128052403, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (127184941..127186382, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene kinesin family member 2A pseudogene Neighboring gene uncharacterized LOC105373333 Neighboring gene zinc finger protein 674 pseudogene Neighboring gene BTG anti-proliferation factor 3 pseudogene 1

Genomic regions, transcripts, and products

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • KIAA0705, MGC26590

Gene Ontology Provided by GOA

Function Evidence Code Pubs
chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
regulation of smoothened signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021358.1 RefSeqGene

    Range
    5001..6442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138289.3NP_612146.1  actin-related protein T1

    See identical proteins and their annotated locations for NP_612146.1

    Status: REVIEWED

    Source sequence(s)
    BC014597, DB452140, DB510229
    Consensus CDS
    CCDS14611.1
    UniProtKB/Swiss-Prot
    Q8TDG2
    Related
    ENSP00000360165.3, ENST00000371124.4
    Conserved Domains (1) summary
    smart00268
    Location:9376
    ACTIN; Actin

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    128050962..128052403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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