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ZFP92 ZFP92 zinc finger protein [ Homo sapiens (human) ]

Gene ID: 139735, updated on 17-Sep-2020

Summary

Official Symbol
ZFP92provided by HGNC
Official Full Name
ZFP92 zinc finger proteinprovided by HGNC
Primary source
HGNC:HGNC:12865
See related
Ensembl:ENSG00000189420
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF897
Expression
Broad expression in ovary (RPKM 2.1), bone marrow (RPKM 1.1) and 19 other tissues See more
Orthologs

Genomic context

See ZFP92 in Genome Data Viewer
Location:
Xq28
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (153411461..153426481)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (152676957..152691939)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene zinc finger protein 275 Neighboring gene uncharacterized LOC105373378 Neighboring gene uncharacterized LOC105373379 Neighboring gene PNMA family member 6E Neighboring gene RNA, 7SL, cytoplasmic 667, pseudogene Neighboring gene three prime repair exonuclease 2 Neighboring gene HAUS augmin like complex subunit 7 Neighboring gene Sharpr-MPRA regulatory region 9358

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 92 homolog
Names
zinc finger protein homologous to Zfp92 in mouse

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136273.2NP_001129745.1  zinc finger protein 92 homolog isoform 1

    See identical proteins and their annotated locations for NP_001129745.1

    Status: VALIDATED

    Source sequence(s)
    U82695
    Consensus CDS
    CCDS59177.1
    UniProtKB/Swiss-Prot
    A6NM28
    Related
    ENSP00000462054.1, ENST00000338647.6
    Conserved Domains (6) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:145286
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:154174
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:264286
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:194219
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001386943.1NP_001373872.1  zinc finger protein 92 homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    U82695
  3. NM_001386944.1NP_001373873.1  zinc finger protein 92 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    U82695
  4. NM_001386945.1NP_001373874.1  zinc finger protein 92 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    U82695

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    153411461..153426481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017029281.1XP_016884770.1  zinc finger protein 92 homolog isoform X1

    Conserved Domains (6) summary
    smart00349
    Location:110170
    KRAB; krueppel associated box
    COG5048
    Location:144406
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:250270
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:360382
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:110149
    KRAB; KRAB box
    pfam13465
    Location:290315
    zf-H2C2_2; Zinc-finger double domain
  2. XM_005274652.3XP_005274709.1  zinc finger protein 92 homolog isoform X2

    See identical proteins and their annotated locations for XP_005274709.1

    UniProtKB/Swiss-Prot
    A6NM28
    Conserved Domains (6) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:145286
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:154174
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:264286
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:194219
    zf-H2C2_2; Zinc-finger double domain
  3. XM_011531115.2XP_011529417.1  zinc finger protein 92 homolog isoform X2

    See identical proteins and their annotated locations for XP_011529417.1

    UniProtKB/Swiss-Prot
    A6NM28
    Conserved Domains (6) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:145286
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:154174
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:264286
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:194219
    zf-H2C2_2; Zinc-finger double domain
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