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MAGEB10 MAGE family member B10 [ Homo sapiens (human) ]

Gene ID: 139422, updated on 11-Jun-2021

Summary

Official Symbol
MAGEB10provided by HGNC
Official Full Name
MAGE family member B10provided by HGNC
Primary source
HGNC:HGNC:25377
See related
Ensembl:ENSG00000177689 MIM:300761
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a member of the B subfamily of the melanoma associated antigen protein family. The encoded protein is specifically expressed in testis and tumor cells. [provided by RefSeq, Apr 2010]
Expression
Restricted expression toward testis (RPKM 1.6) See more
Orthologs
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Genomic context

See MAGEB10 in Genome Data Viewer
Location:
Xp21.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (27807990..27823014)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (27826107..27841131)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene protein phosphatase 4 regulatory subunit 3C Neighboring gene DDB1 and CUL4 associated factor 8 like 2 Neighboring gene radixin pseudogene 2 Neighboring gene RDX pseudogene 3 Neighboring gene MAGE family member B18 pseudogene Neighboring gene MAGE family member B3 pseudogene Neighboring gene MAGE family member B4 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32965, MGC120394

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
melanoma-associated antigen B10
Names
MAGE family testis and tumor-specific protein
MAGE-B10 antigen
melanoma antigen family B, 10
melanoma antigen family B10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_017094.1 RefSeqGene

    Range
    5007..20031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_182506.3NP_872312.2  melanoma-associated antigen B10

    See identical proteins and their annotated locations for NP_872312.2

    Status: REVIEWED

    Source sequence(s)
    AC112492, AK057527, BC101308
    Consensus CDS
    CCDS35221.1
    UniProtKB/Swiss-Prot
    Q96LZ2
    Related
    ENSP00000368304.1, ENST00000356790.2
    Conserved Domains (2) summary
    pfam01454
    Location:118286
    MAGE; MAGE family
    pfam12440
    Location:593
    MAGE_N; Melanoma associated antigen family N terminal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    27807990..27823014
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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