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FUNDC1 FUN14 domain containing 1 [ Homo sapiens (human) ]

Gene ID: 139341, updated on 21-Dec-2019

Summary

Official Symbol
FUNDC1provided by HGNC
Official Full Name
FUN14 domain containing 1provided by HGNC
Primary source
HGNC:HGNC:28746
See related
Ensembl:ENSG00000069509 MIM:300871
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011]
Expression
Ubiquitous expression in brain (RPKM 11.4), heart (RPKM 11.0) and 25 other tissues See more
Orthologs

Genomic context

See FUNDC1 in Genome Data Viewer
Location:
Xp11.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (44523639..44542859, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (44382885..44402221, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ubinuclein 1 pseudogene Neighboring gene farnesyl diphosphate synthase pseudogene 5 Neighboring gene chromosome transmission fidelity factor 8 pseudogene 1 Neighboring gene ribosomal protein L19 pseudogene 20

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC51029

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
autophagy of mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
autophagy of mitochondrion IGI
Inferred from Genetic Interaction
more info
PubMed 
autophagy of mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 
macroautophagy TAS
Traceable Author Statement
more info
 
response to hypoxia IDA
Inferred from Direct Assay
more info
PubMed 
response to hypoxia IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to organonitrogen compound IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of mitochondrial outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial outer membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
FUN14 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021288.1 RefSeqGene

    Range
    5117..24337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_173794.4NP_776155.1  FUN14 domain-containing protein 1

    See identical proteins and their annotated locations for NP_776155.1

    Status: REVIEWED

    Source sequence(s)
    BC035015, BG213042, BM837991
    Consensus CDS
    CCDS14263.1
    UniProtKB/Swiss-Prot
    Q8IVP5
    Related
    ENSP00000367284.4, ENST00000378045.5
    Conserved Domains (1) summary
    pfam04930
    Location:54153
    FUN14; FUN14 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    44523639..44542859 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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