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ARID3C AT-rich interaction domain 3C [ Homo sapiens (human) ]

Gene ID: 138715, updated on 13-Mar-2020

Summary

Official Symbol
ARID3Cprovided by HGNC
Official Full Name
AT-rich interaction domain 3Cprovided by HGNC
Primary source
HGNC:HGNC:21209
See related
Ensembl:ENSG00000205143
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene is a member of the ARID (AT-rich interaction domain) family of proteins. The ARID domain is a helix-turn-helix motif-based DNA-binding domain. ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See ARID3C in Genome Data Viewer
Location:
9p13.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (34621049..34633112, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (34621455..34628011, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene ribonuclease P/MRP subunit p25 like Neighboring gene dynactin subunit 3 Neighboring gene sigma non-opioid intracellular receptor 1 Neighboring gene galactose-1-phosphate uridylyltransferase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromatin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
AT-rich interactive domain-containing protein 3C
Names
ARID domain-containing protein 3C
AT rich interactive domain 3C (BRIGHT-like)
Brightlike

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017363.2NP_001017363.1  AT-rich interactive domain-containing protein 3C isoform 1

    See identical proteins and their annotated locations for NP_001017363.1

    Status: REVIEWED

    Source sequence(s)
    AL450283
    Consensus CDS
    CCDS35006.1
    UniProtKB/Swiss-Prot
    A6NKF2
    Related
    ENSP00000368189.2, ENST00000378909.3
    Conserved Domains (1) summary
    smart00501
    Location:114205
    BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
  2. NM_001371945.1NP_001358874.1  AT-rich interactive domain-containing protein 3C isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL450283

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    34621049..34633112 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017014283.1XP_016869772.1  AT-rich interactive domain-containing protein 3C isoform X1

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