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ARID3C AT-rich interaction domain 3C [ Homo sapiens (human) ]

Gene ID: 138715, updated on 23-Nov-2021

Summary

Official Symbol
ARID3Cprovided by HGNC
Official Full Name
AT-rich interaction domain 3Cprovided by HGNC
Primary source
HGNC:HGNC:21209
See related
Ensembl:ENSG00000205143
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene is a member of the ARID (AT-rich interaction domain) family of proteins. The ARID domain is a helix-turn-helix motif-based DNA-binding domain. ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See ARID3C in Genome Data Viewer
Location:
9p13.3
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (34621049..34629066, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (34621046..34629052, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene ribonuclease P/MRP subunit p25 like Neighboring gene dynactin subunit 3 Neighboring gene sigma non-opioid intracellular receptor 1 Neighboring gene Sharpr-MPRA regulatory region 8240

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
AT-rich interactive domain-containing protein 3C
Names
ARID domain-containing protein 3C
AT rich interactive domain 3C (BRIGHT-like)
Brightlike

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017363.4NP_001017363.1  AT-rich interactive domain-containing protein 3C isoform 1

    See identical proteins and their annotated locations for NP_001017363.1

    Status: VALIDATED

    Source sequence(s)
    AL450283
    Consensus CDS
    CCDS35006.1
    UniProtKB/Swiss-Prot
    A6NKF2
    Related
    ENSP00000368189.2, ENST00000378909.3
    Conserved Domains (1) summary
    cl28902
    Location:101227
    ARID; ARID/BRIGHT DNA binding domain family
  2. NM_001371945.2NP_001358874.1  AT-rich interactive domain-containing protein 3C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL450283
    Conserved Domains (1) summary
    cd16880
    Location:101227
    ARID_ARID3C; ARID/BRIGHT DNA binding domain of AT-rich interactive domain-containing protein 3C (ARID3C) and similar proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    34621049..34629066 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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