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Emx1 empty spiracles homeobox 1 [ Mus musculus (house mouse) ]

Gene ID: 13796, updated on 21-Jan-2020

Summary

Official Symbol
Emx1provided by MGI
Official Full Name
empty spiracles homeobox 1provided by MGI
Primary source
MGI:MGI:95387
See related
Ensembl:ENSMUSG00000033726
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Biased expression in kidney adult (RPKM 30.5), CNS E14 (RPKM 18.1) and 5 other tissues See more
Orthologs

Genomic context

See Emx1 in Genome Data Viewer
Location:
6 C3; 6 37.21 cM
Exon count:
3
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (85187931..85204463)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (85137925..85154457)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene sepiapterin reductase pseudogene 1 Neighboring gene predicted gene, 33200 Neighboring gene sideroflexin 5 Neighboring gene RAB11 family interacting protein 5 (class I) Neighboring gene microRNA 705

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC129284, MGC129285

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
brain development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
brain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
brain morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
central nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cerebral cortex development IGI
Inferred from Genetic Interaction
more info
PubMed 
cerebral cortex development IMP
Inferred from Mutant Phenotype
more info
PubMed 
cerebral cortex neuron differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
cerebral cortex regionalization IGI
Inferred from Genetic Interaction
more info
PubMed 
homeostasis of number of cells IGI
Inferred from Genetic Interaction
more info
PubMed 
in utero embryonic development IGI
Inferred from Genetic Interaction
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
neuroepithelial cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron projection extension IGI
Inferred from Genetic Interaction
more info
PubMed 
post-embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
radial glial cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of oligodendrocyte progenitor proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to drug IDA
Inferred from Direct Assay
more info
PubMed 
telencephalon development IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
homeobox protein EMX1
Names
empty spiracles homolog 1
empty spiracles-like protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010131.2NP_034261.1  homeobox protein EMX1

    See identical proteins and their annotated locations for NP_034261.1

    Status: VALIDATED

    Source sequence(s)
    AB221645, AC153605, BE865010, CO039530
    Consensus CDS
    CCDS20290.1
    UniProtKB/Swiss-Prot
    Q04742
    Related
    ENSMUSP00000046026.8, ENSMUST00000045942.8
    Conserved Domains (2) summary
    COG5576
    Location:108218
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:163215
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p6 C57BL/6J

    Range
    85187931..85204463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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