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LYPD2 LY6/PLAUR domain containing 2 [ Homo sapiens (human) ]

Gene ID: 137797, updated on 18-Aug-2020

Summary

Official Symbol
LYPD2provided by HGNC
Official Full Name
LY6/PLAUR domain containing 2provided by HGNC
Primary source
HGNC:HGNC:25215
See related
Ensembl:ENSG00000197353
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LYPDC2; UNQ430
Expression
Biased expression in esophagus (RPKM 24.8), stomach (RPKM 10.7) and 1 other tissue See more
Orthologs

Genomic context

See LYPD2 in Genome Data Viewer
Location:
8q24.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (142750150..142752532, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (143831628..143833952, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene thioesterase superfamily member 6 Neighboring gene secreted LY6/PLAUR domain containing 1 Neighboring gene LYNX1-SLURP2 readthrough Neighboring gene secreted LY6/PLAUR domain containing 2 Neighboring gene Ly6/neurotoxin 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC148106

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
ly6/PLAUR domain-containing protein 2
Names
RGTR430

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205545.3NP_991108.1  ly6/PLAUR domain-containing protein 2 precursor

    See identical proteins and their annotated locations for NP_991108.1

    Status: VALIDATED

    Source sequence(s)
    AY358432, DA449804
    Consensus CDS
    CCDS6388.1
    UniProtKB/Swiss-Prot
    Q6UXB3
    UniProtKB/TrEMBL
    F1T0L0
    Related
    ENSP00000352163.3, ENST00000359228.4
    Conserved Domains (1) summary
    cd00117
    Location:23102
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    142750150..142752532 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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