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Emb embigin [ Mus musculus (house mouse) ]

Gene ID: 13723, updated on 26-Mar-2024

Summary

Official Symbol
Embprovided by MGI
Official Full Name
embiginprovided by MGI
Primary source
MGI:MGI:95321
See related
Ensembl:ENSMUSG00000021728 AllianceGenome:MGI:95321
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gp70
Summary
Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules; neuron development; and plasma membrane lactate transport. Predicted to be integral component of plasma membrane. Predicted to be active in axon and plasma membrane. Is expressed in several structures, including alimentary system; ectoderm; egg cylinder; genitourinary system; and nervous system. Orthologous to human EMB (embigin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 29.7), genital fat pad adult (RPKM 29.2) and 23 other tissues See more
Orthologs
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Genomic context

See Emb in Genome Data Viewer
Location:
13 D2.3; 13 65.4 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (117357109..117410951)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (117220573..117274415)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene 6416 Neighboring gene elongation protein 4 homolog pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:118004988-118005274 Neighboring gene STARR-seq mESC enhancer starr_35777 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:118009934-118010043 Neighboring gene predicted gene, 17509 Neighboring gene ring finger protein 7 pseudogene Neighboring gene STARR-seq mESC enhancer starr_35778 Neighboring gene H3 histone, family 3A pseudogene Neighboring gene keratin 18 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (3)  1 citation
  • Endonuclease-mediated (5) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC21425

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cell-cell adhesion mediator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 
involved_in cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in dendrite self-avoidance IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in plasma membrane lactate transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
embigin
Names
glycoprotein 70
teratocarcinoma glycoprotein Gp-70

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010330.4NP_034460.3  embigin precursor

    See identical proteins and their annotated locations for NP_034460.3

    Status: VALIDATED

    Source sequence(s)
    AK138271, AK148540, BY077584, CJ085726
    Consensus CDS
    CCDS26791.1
    UniProtKB/Swiss-Prot
    P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38
    UniProtKB/TrEMBL
    Q3TSZ8, Q3UFK0
    Related
    ENSMUSP00000022242.8, ENSMUST00000022242.9
    Conserved Domains (2) summary
    cd00096
    Location:179250
    Ig; Immunoglobulin domain
    smart00410
    Location:168257
    IG_like; Immunoglobulin like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    117357109..117410951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)