Format

Send to:

Choose Destination

SVOPL SVOP like [ Homo sapiens (human) ]

Gene ID: 136306, updated on 5-Jan-2022

Summary

Official Symbol
SVOPLprovided by HGNC
Official Full Name
SVOP likeprovided by HGNC
Primary source
HGNC:HGNC:27034
See related
Ensembl:ENSG00000157703 MIM:611700
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene is thought to be a member of solute carrier family 22, which includes transmembrane proteins that transport toxins and drugs from the body. This gene is a paralog of the SVOP gene that encodes synaptic vesicle 2-related protein. [provided by RefSeq, Sep 2016]
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SVOPL in Genome Data Viewer
Location:
7q34
Exon count:
19
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (138591689..138701362, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (138279030..138386107, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene inosine monophosphate dehydrogenase 1 pseudogene 3 Neighboring gene tripartite motif containing 24 Neighboring gene RPS3A pseudogene 28 Neighboring gene ribosomal protein L21 pseudogene 73 Neighboring gene ribosomal protein L17 pseudogene 27 Neighboring gene ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 2 Neighboring gene ATPase H+ transporting V0 subunit a4 Neighboring gene transmembrane protein 213

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC46715

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative transporter SVOPL
Names
SV2 related protein homolog-like

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_051552.1 RefSeqGene

    Range
    5186..112263
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_1103

mRNA and Protein(s)

  1. NM_001139456.2NP_001132928.1  putative transporter SVOPL isoform 1

    See identical proteins and their annotated locations for NP_001132928.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC013429, AC020983
    Consensus CDS
    CCDS47721.1
    UniProtKB/Swiss-Prot
    Q8N434
    Related
    ENSP00000501457.1, ENST00000674285.1
    Conserved Domains (2) summary
    cd06174
    Location:51480
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00895
    Location:34454
    2A0115; benzoate transport
  2. NM_001331192.1NP_001318121.1  putative transporter SVOPL isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC013429, AC020983
    Conserved Domains (1) summary
    cl26863
    Location:2397
    Sugar_tr; Sugar (and other) transporter
  3. NM_174959.3NP_777619.1  putative transporter SVOPL isoform 2

    See identical proteins and their annotated locations for NP_777619.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AL704123, BC036796, BX349158
    Consensus CDS
    CCDS5848.1
    UniProtKB/Swiss-Prot
    Q8N434
    Related
    ENSP00000417018.1, ENST00000436657.5
    Conserved Domains (1) summary
    cl26863
    Location:6336
    Sugar_tr; Sugar (and other) transporter

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    138591689..138701362 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011515797.2XP_011514099.1  putative transporter SVOPL isoform X3

    See identical proteins and their annotated locations for XP_011514099.1

    UniProtKB/Swiss-Prot
    Q8N434
    Conserved Domains (1) summary
    cl26863
    Location:6336
    Sugar_tr; Sugar (and other) transporter
  2. XM_024446655.1XP_024302423.1  putative transporter SVOPL isoform X2

    Conserved Domains (1) summary
    cl26863
    Location:2397
    Sugar_tr; Sugar (and other) transporter
  3. XM_017011748.1XP_016867237.1  putative transporter SVOPL isoform X3

    UniProtKB/Swiss-Prot
    Q8N434
    Conserved Domains (1) summary
    cl26863
    Location:6336
    Sugar_tr; Sugar (and other) transporter
  4. XM_017011747.1XP_016867236.1  putative transporter SVOPL isoform X3

    UniProtKB/Swiss-Prot
    Q8N434
    Conserved Domains (1) summary
    cl26863
    Location:6336
    Sugar_tr; Sugar (and other) transporter
  5. XM_024446654.1XP_024302422.1  putative transporter SVOPL isoform X2

    Conserved Domains (1) summary
    cl26863
    Location:2397
    Sugar_tr; Sugar (and other) transporter
Support Center