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SSU72L6 SSU72 like 6 [ Homo sapiens (human) ]

Gene ID: 136157, updated on 17-Jun-2024

Summary

Official Symbol
SSU72L6provided by HGNC
Official Full Name
SSU72 like 6provided by HGNC
Primary source
HGNC:HGNC:43627
See related
Ensembl:ENSG00000230268 AllianceGenome:HGNC:43627
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SSU72P8
Summary
Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in dephosphorylation of RNA polymerase II C-terminal domain; mRNA polyadenylation; and termination of RNA polymerase II transcription. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See SSU72L6 in Genome Data Viewer
Location:
7q31.33
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (124476317..124477664)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (125793835..125795182)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (124116425..124117009)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986841 Neighboring gene uncharacterized LOC101928211 Neighboring gene MPRA-validated peak6707 silencer Neighboring gene MPRA-validated peak6708 silencer Neighboring gene uncharacterized LOC102724577 Neighboring gene MPRA-validated peak6710 silencer Neighboring gene MPRA-validated peak6711 silencer Neighboring gene NANOG hESC enhancer GRCh37_chr7:124085682-124086183 Neighboring gene ribosomal protein S2 pseudogene 31 Neighboring gene RNA, U6 small nuclear 102, pseudogene

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in termination of RNA polymerase II transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of mRNA cleavage and polyadenylation specificity factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 6
Names
CTD phosphatase SSU72L6
RNA polymerase II subunit A C-terminal domain phosphatase SSU72L6
SSU72 RNA polymerase II CTD phosphatase homolog pseudogene 8
SSU72 pseudogene 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001414004.1NP_001400933.1  RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 6

    Status: VALIDATED

    Source sequence(s)
    AC005521, KF458590
    UniProtKB/Swiss-Prot
    A0A1W2PR75
    Related
    ENSP00000492512.1, ENST00000473520.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    124476317..124477664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    125793835..125795182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_012760.1: Suppressed sequence

    Description
    NG_012760.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
  2. NM_001085395.2: Suppressed sequence

    Description
    NM_001085395.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.