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Reep5 receptor accessory protein 5 [ Mus musculus (house mouse) ]

Gene ID: 13476, updated on 1-Mar-2024

Summary

Official Symbol
Reep5provided by MGI
Official Full Name
receptor accessory protein 5provided by MGI
Primary source
MGI:MGI:1270152
See related
Ensembl:ENSMUSG00000005873 AllianceGenome:MGI:1270152
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dp1; DP1/TB2; TB2/DP1
Summary
Located in endoplasmic reticulum tubular network. Is expressed in early conceptus; nervous system; pancreas; and secondary oocyte. Orthologous to human REEP5 (receptor accessory protein 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 93.0), subcutaneous fat pad adult (RPKM 90.5) and 27 other tissues See more
Orthologs
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Genomic context

See Reep5 in Genome Data Viewer
Location:
18 B1; 18 18.57 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (34477938..34508044, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (34344885..34374991, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene APC, WNT signaling pathway regulator Neighboring gene predicted gene, 54017 Neighboring gene signal recognition particle 19 Neighboring gene STARR-positive B cell enhancer ABC_E8999 Neighboring gene polycystic kidney disease 2-like 2 Neighboring gene SET translocation pseudogene Neighboring gene family with sequence similarity 13, member B Neighboring gene STARR-seq mESC enhancer starr_44201 Neighboring gene STARR-seq mESC enhancer starr_44203 Neighboring gene STARR-seq mESC enhancer starr_44204

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum membrane organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum tubular network IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum tubular network ISO
Inferred from Sequence Orthology
more info
 
located_in junctional sarcoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in sarcoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in sarcoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
receptor expression-enhancing protein 5
Names
GP106
deleted in polyposis 1
polyposis locus protein 1 homolog
protein TB2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007874.3NP_031900.3  receptor expression-enhancing protein 5

    See identical proteins and their annotated locations for NP_031900.3

    Status: VALIDATED

    Source sequence(s)
    AI842075, AK013146, BU053115
    Consensus CDS
    CCDS50247.1
    UniProtKB/TrEMBL
    G3X8R0, Q5QGU0
    Related
    ENSMUSP00000006027.6, ENSMUST00000006027.7
    Conserved Domains (1) summary
    pfam03134
    Location:55143
    TB2_DP1_HVA22; TB2/DP1, HVA22 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    34477938..34508044 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_003952491.2 RNA Sequence