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SOWAHA sosondowah ankyrin repeat domain family member A [ Homo sapiens (human) ]

Gene ID: 134548, updated on 17-Sep-2024

Summary

Official Symbol
SOWAHAprovided by HGNC
Official Full Name
sosondowah ankyrin repeat domain family member Aprovided by HGNC
Primary source
HGNC:HGNC:27033
See related
Ensembl:ENSG00000198944 AllianceGenome:HGNC:27033
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ANKRD43
Orthologs
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Genomic context

See SOWAHA in Genome Data Viewer
Location:
5q31.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (132813302..132816786)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (133333040..133336524)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (132148994..132152478)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene kinesin family member 3A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23094 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16332 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23095 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16333 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16334 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16335 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23096 Neighboring gene septin 8 Neighboring gene cyclin I family member 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16336 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16337 Neighboring gene Sharpr-MPRA regulatory region 2681 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16338 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:132150138-132150638 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:132150639-132151139 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16339 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16340 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16341 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16342 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16343 Neighboring gene shroom family member 1 Neighboring gene U7 small nuclear RNA Neighboring gene RNA, U7 small nuclear 15 pseudogene

Genomic regions, transcripts, and products

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of sosondowah ankyrin repeat domain family member A (SOWAHA; ANKRD43) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

General protein information

Preferred Names
ankyrin repeat domain-containing protein SOWAHA
Names
ankyrin repeat domain-containing protein 43
protein sosondowah homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175873.6NP_787069.4  ankyrin repeat domain-containing protein SOWAHA precursor

    Status: VALIDATED

    Source sequence(s)
    AC004775, KC877113
    Consensus CDS
    CCDS43361.1
    UniProtKB/Swiss-Prot
    Q2M3V2, Q8NAE7
    Related
    ENSP00000367965.2, ENST00000378693.4
    Conserved Domains (3) summary
    cd00204
    Location:346438
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam13637
    Location:346405
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:345382
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    132813302..132816786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    133333040..133336524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)