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Dnm2 dynamin 2 [ Mus musculus (house mouse) ]

Gene ID: 13430, updated on 18-Sep-2018

Summary

Official Symbol
Dnm2provided by MGI
Official Full Name
dynamin 2provided by MGI
Primary source
MGI:MGI:109547
See related
Ensembl:ENSMUSG00000033335 Vega:OTTMUSG00000038087
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dyn2; Udnm; b2b2159Clo
Expression
Ubiquitous expression in duodenum adult (RPKM 68.5), colon adult (RPKM 65.8) and 28 other tissues See more
Orthologs

Genomic context

See Dnm2 in Genome Data Viewer
Location:
9 A3; 9 7.79 cM
Exon count:
25
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (21424908..21507759)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21229389..21311568)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36198 Neighboring gene interleukin enhancer binding factor 3 Neighboring gene predicted gene, 16853 Neighboring gene queuine tRNA-ribosyltransferase catalytic subunit 1 Neighboring gene predicted gene, 46104 Neighboring gene microRNA 199a-1 Neighboring gene transmembrane p24 trafficking protein 1 Neighboring gene cDNA sequence AB124611 Neighboring gene coactivator-associated arginine methyltransferase 1 Neighboring gene Yip1 domain family, member 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (2) 
  • Targeted (5)  1 citation
  • Chemically induced (ENU) (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
D2 dopamine receptor binding ISO
Inferred from Sequence Orthology
more info
 
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity ISO
Inferred from Sequence Orthology
more info
 
SH3 domain binding ISO
Inferred from Sequence Orthology
more info
 
WW domain binding ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nitric-oxide synthase binding ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol 3-kinase regulatory subunit binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G protein-coupled receptor internalization ISO
Inferred from Sequence Orthology
more info
 
Golgi to plasma membrane transport ISO
Inferred from Sequence Orthology
more info
 
aorta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to dopamine ISO
Inferred from Sequence Orthology
more info
 
coronary vasculature development IMP
Inferred from Mutant Phenotype
more info
PubMed 
endocytosis IEA
Inferred from Electronic Annotation
more info
 
macropinocytosis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of membrane tubulation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of non-motile cilium assembly ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transforming growth factor beta receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
neuron projection morphogenesis ISO
Inferred from Sequence Orthology
more info
 
phagocytosis IEA
Inferred from Electronic Annotation
more info
 
positive regulation of clathrin-dependent endocytosis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of endocytosis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of lamellipodium assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of nitric oxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of phagocytosis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of sodium:potassium-exchanging ATPase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of substrate adhesion-dependent cell spreading ISO
Inferred from Sequence Orthology
more info
 
postsynaptic neurotransmitter receptor internalization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor internalization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor internalization ISO
Inferred from Sequence Orthology
more info
 
receptor-mediated endocytosis ISO
Inferred from Sequence Orthology
more info
 
regulation of Golgi organization ISO
Inferred from Sequence Orthology
more info
 
regulation of Rac protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
regulation of axon extension ISO
Inferred from Sequence Orthology
more info
 
regulation of synapse structure or activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle budding from presynaptic endocytic zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
synaptic vesicle endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
transferrin transport ISO
Inferred from Sequence Orthology
more info
 
ventricular septum development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell junction ISO
Inferred from Sequence Orthology
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
centrosome ISO
Inferred from Sequence Orthology
more info
 
clathrin-coated endocytic vesicle ISO
Inferred from Sequence Orthology
more info
 
clathrin-coated pit ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendritic spine head IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endosome ISO
Inferred from Sequence Orthology
more info
 
glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with growth cone ISO
Inferred from Sequence Orthology
more info
 
lamellipodium ISO
Inferred from Sequence Orthology
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
phagocytic cup ISO
Inferred from Sequence Orthology
more info
 
photoreceptor inner segment IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postsynaptic density, intracellular component ISO
Inferred from Sequence Orthology
more info
 
postsynaptic endocytic zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postsynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postsynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
ruffle membrane ISO
Inferred from Sequence Orthology
more info
 
synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dynamin-2
NP_001034609.1
NP_001240822.1
NP_001240823.1
NP_031897.2
XP_006510036.1
XP_006510037.1
XP_006510038.1
XP_006510039.1
XP_006510040.1
XP_006510041.1
XP_006510042.1
XP_006510043.1
XP_006510044.1
XP_006510045.1
XP_006510046.1
XP_006510047.1
XP_006510048.1
XP_017168614.1
XP_017168615.1
XP_017168616.1
XP_017168617.1
XP_017168618.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039520.2NP_001034609.1  dynamin-2 isoform 2

    See identical proteins and their annotated locations for NP_001034609.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    AA221527, AK157844, AK171566, BY275016
    Consensus CDS
    CCDS57660.1
    UniProtKB/TrEMBL
    Q3TCR7
    Related
    ENSMUSP00000134243.1, OTTMUSP00000055074, ENSMUST00000173397.7, OTTMUST00000098110
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651739
    GED; Dynamin GTPase effector domain
    cl26386
    Location:745865
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  2. NM_001253893.1NP_001240822.1  dynamin-2 isoform 1

    See identical proteins and their annotated locations for NP_001240822.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest variant and it encodes the longest protein (isoform 1).
    Source sequence(s)
    AA221527, AK005012, AK150046, AK157844, BY275016, BY549643
    Consensus CDS
    CCDS57657.1
    UniProtKB/Swiss-Prot
    P39054
    Related
    ENSMUSP00000133564.1, OTTMUSP00000055080, ENSMUST00000172482.7, OTTMUST00000098121
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651739
    GED; Dynamin GTPase effector domain
    cl26464
    Location:737868
    Atrophin-1; Atrophin-1 family
  3. NM_001253894.1NP_001240823.1  dynamin-2 isoform 4

    See identical proteins and their annotated locations for NP_001240823.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains an alternate 3' terminal exon compared to variant 1. The resulting protein (isoform 4) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK005012, BQ031151, BY275016, CD540553
    Consensus CDS
    CCDS57658.1
    UniProtKB/Swiss-Prot
    P39054
    UniProtKB/TrEMBL
    Q3T9X3
    Related
    ENSMUSP00000128961.2, OTTMUSP00000055073, ENSMUST00000165766.8, OTTMUST00000098109
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651739
    GED; Dynamin GTPase effector domain
    cl26464
    Location:737836
    Atrophin-1; Atrophin-1 family
  4. NM_001357718.1NP_001344647.1  dynamin-2 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an alternate exon and contains another alternate exon compared to variant 1. The resulting isoform (5) has the same N- and C-termini and the same length but differs in an internal segment compared to isoform 1.
    Source sequence(s)
    AC163748
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651739
    GED; Dynamin GTPase effector domain
    cl26464
    Location:737868
    Atrophin-1; Atrophin-1 family
  5. NM_001357719.1NP_001344648.1  dynamin-2 isoform 6

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an alternate in-frame exon and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (6) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC163748
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:514625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647735
    GED; Dynamin GTPase effector domain
    cl26464
    Location:733832
    Atrophin-1; Atrophin-1 family
  6. NM_001357721.1NP_001344650.1  dynamin-2 isoform 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks two alternate exons, contains another alternate exon, and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (7) lacks an alternate internal segment, differs in another internal segment, and has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC163748
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:514625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647735
    GED; Dynamin GTPase effector domain
    cl26464
    Location:733832
    Atrophin-1; Atrophin-1 family
  7. NM_007871.2NP_031897.2  dynamin-2 isoform 3

    See identical proteins and their annotated locations for NP_031897.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate exon in the coding region compared to variant 1. The resulting protein (isoform 3) is shorter but has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    AA221527, AK005012, AK157844, BY275016, BY549643
    Consensus CDS
    CCDS57659.1
    UniProtKB/Swiss-Prot
    P39054
    Related
    ENSMUSP00000088616.6, OTTMUSP00000055076, ENSMUST00000091087.12, OTTMUST00000098112
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:514625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647735
    GED; Dynamin GTPase effector domain
    cl26464
    Location:733864
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    21424908..21507759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006509984.3XP_006510047.1  dynamin-2 isoform X17

    Conserved Domains (3) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    COG0699
    Location:78498
    CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
    pfam01031
    Location:217498
    Dynamin_M; Dynamin central region
  2. XM_006509978.2XP_006510041.1  dynamin-2 isoform X7

    Conserved Domains (7) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    COG0699
    Location:78498
    CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
    cd01256
    Location:530639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam00169
    Location:530633
    PH; PH domain
    pfam01031
    Location:217498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661749
    GED; Dynamin GTPase effector domain
    pfam16666
    Location:768830
    MAGI_u5; Unstructured region on MAGI
  3. XM_017313126.1XP_017168615.1  dynamin-2 isoform X10

  4. XM_006509982.2XP_006510045.1  dynamin-2 isoform X14

    Related
    ENSMUSP00000134696.1, OTTMUSP00000055077, ENSMUST00000174050.7, OTTMUST00000098113
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:514625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647735
    GED; Dynamin GTPase effector domain
    cl26464
    Location:733832
    Atrophin-1; Atrophin-1 family
  5. XM_006509981.2XP_006510044.1  dynamin-2 isoform X13

    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651739
    GED; Dynamin GTPase effector domain
    cl26464
    Location:737836
    Atrophin-1; Atrophin-1 family
  6. XM_017313129.1XP_017168618.1  dynamin-2 isoform X15

    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:514625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647735
    GED; Dynamin GTPase effector domain
    cl26464
    Location:733832
    Atrophin-1; Atrophin-1 family
  7. XM_006509976.2XP_006510039.1  dynamin-2 isoform X4

    Conserved Domains (7) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    COG0699
    Location:78498
    CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
    cd01256
    Location:524635
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam00169
    Location:526629
    PH; PH domain
    pfam01031
    Location:217498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:657745
    GED; Dynamin GTPase effector domain
    pfam16666
    Location:764826
    MAGI_u5; Unstructured region on MAGI
  8. XM_017313125.1XP_017168614.1  dynamin-2 isoform X5

  9. XM_017313127.1XP_017168616.1  dynamin-2 isoform X11

  10. XM_006509980.2XP_006510043.1  dynamin-2 isoform X9

    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:514625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647735
    GED; Dynamin GTPase effector domain
    cl26464
    Location:733864
    Atrophin-1; Atrophin-1 family
  11. XM_017313128.1XP_017168617.1  dynamin-2 isoform X12

    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:514625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647735
    GED; Dynamin GTPase effector domain
    cl26386
    Location:741861
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  12. XM_006509973.1XP_006510036.1  dynamin-2 isoform X1

    Conserved Domains (7) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    COG0699
    Location:78498
    CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
    cd01256
    Location:530639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam00169
    Location:530633
    PH; PH domain
    pfam01031
    Location:217498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661749
    GED; Dynamin GTPase effector domain
    pfam16666
    Location:768830
    MAGI_u5; Unstructured region on MAGI
  13. XM_006509975.1XP_006510038.1  dynamin-2 isoform X3

    Conserved Domains (7) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    COG0699
    Location:78498
    CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
    cd01256
    Location:530639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam00169
    Location:530633
    PH; PH domain
    pfam01031
    Location:217498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661749
    GED; Dynamin GTPase effector domain
    pfam16666
    Location:768830
    MAGI_u5; Unstructured region on MAGI
  14. XM_006509979.1XP_006510042.1  dynamin-2 isoform X8

    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651739
    GED; Dynamin GTPase effector domain
    cl26386
    Location:745865
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  15. XM_006509974.1XP_006510037.1  dynamin-2 isoform X2

    Conserved Domains (7) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    COG0699
    Location:78498
    CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
    cd01256
    Location:530639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam00169
    Location:530633
    PH; PH domain
    pfam01031
    Location:217498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661749
    GED; Dynamin GTPase effector domain
    pfam16666
    Location:768830
    MAGI_u5; Unstructured region on MAGI
  16. XM_006509977.1XP_006510040.1  dynamin-2 isoform X6

    UniProtKB/TrEMBL
    G3X9G4
    Related
    ENSMUSP00000072199.7, OTTMUSP00000055075, ENSMUST00000072362.13, OTTMUST00000098111
    Conserved Domains (5) summary
    smart00053
    Location:6245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216501
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651739
    GED; Dynamin GTPase effector domain
    cl26464
    Location:737868
    Atrophin-1; Atrophin-1 family
  17. XM_006509983.1XP_006510046.1  dynamin-2 isoform X16

    Conserved Domains (7) summary
    COG0699
    Location:1340
    CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
    cd01256
    Location:372481
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam00169
    Location:372475
    PH; PH domain
    pfam01031
    Location:59340
    Dynamin_M; Dynamin central region
    pfam02212
    Location:503591
    GED; Dynamin GTPase effector domain
    pfam16666
    Location:610672
    MAGI_u5; Unstructured region on MAGI
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  18. XM_006509985.3XP_006510048.1  dynamin-2 isoform X18

    Conserved Domains (5) summary
    cd01256
    Location:124233
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam00169
    Location:124227
    PH; PH domain
    pfam01031
    Location:192
    Dynamin_M; Dynamin central region
    pfam02212
    Location:255343
    GED; Dynamin GTPase effector domain
    pfam16666
    Location:362424
    MAGI_u5; Unstructured region on MAGI

RNA

  1. XR_001778793.1 RNA Sequence

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