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Dmp1 dentin matrix protein 1 [ Mus musculus (house mouse) ]

Gene ID: 13406, updated on 14-Oct-2018

Summary

Official Symbol
Dmp1provided by MGI
Official Full Name
dentin matrix protein 1provided by MGI
Primary source
MGI:MGI:94910
See related
Ensembl:ENSMUSG00000029307 Vega:OTTMUSG00000053772
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PP; AG1; Dmp; DMP-1; AV020965
Expression
Biased expression in cerebellum adult (RPKM 1.9), frontal lobe adult (RPKM 1.1) and 8 other tissues See more
Orthologs

Genomic context

See Dmp1 in Genome Data Viewer
Location:
5 E5; 5 50.61 cM
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (104197558..104214109)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (104631636..104643121)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein-like 9 pseudogene Neighboring gene dentin sialophosphoprotein Neighboring gene predicted gene, 31048 Neighboring gene integrin binding sialoprotein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC130441

Gene Ontology Provided by MGI

Function Evidence Code Pubs
Hsp70 protein binding ISO
Inferred from Sequence Orthology
more info
 
extracellular matrix binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
biomineral tissue development IEA
Inferred from Electronic Annotation
more info
 
extracellular matrix organization IDA
Inferred from Direct Assay
more info
PubMed 
ossification IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell-substrate adhesion IDA
Inferred from Direct Assay
more info
PubMed 
regulation of enamel mineralization IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
extracellular matrix IDA
Inferred from Direct Assay
more info
PubMed 
extracellular matrix ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
dentin matrix acidic phosphoprotein 1
Names
serine rich acidic phosphoprotein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359013.1NP_001345942.1  dentin matrix acidic phosphoprotein 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC164587
    Conserved Domains (1) summary
    pfam07263
    Location:1503
    DMP1; Dentin matrix protein 1 (DMP1)
  2. NM_016779.2NP_058059.2  dentin matrix acidic phosphoprotein 1 precursor

    See identical proteins and their annotated locations for NP_058059.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AK132177
    Consensus CDS
    CCDS19484.1
    UniProtKB/Swiss-Prot
    O55188
    Related
    ENSMUSP00000068053.5, OTTMUSP00000071084, ENSMUST00000066708.6, OTTMUST00000133853
    Conserved Domains (1) summary
    pfam07263
    Location:1503
    DMP1; Dentin matrix protein 1 (DMP1)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    104197558..104214109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534766.2XP_006534829.1  dentin matrix acidic phosphoprotein 1 isoform X1

    UniProtKB/Swiss-Prot
    O55188
    Conserved Domains (1) summary
    pfam07263
    Location:1503
    DMP1; Dentin matrix protein 1 (DMP1)
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