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MROH2B maestro heat like repeat family member 2B [ Homo sapiens (human) ]

Gene ID: 133558, updated on 23-Nov-2021

Summary

Official Symbol
MROH2Bprovided by HGNC
Official Full Name
maestro heat like repeat family member 2Bprovided by HGNC
Primary source
HGNC:HGNC:26857
See related
Ensembl:ENSG00000171495
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SPIF; HEATR7B2
Expression
Restricted expression toward testis (RPKM 23.2) See more
Orthologs
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Genomic context

See MROH2B in Genome Data Viewer
Location:
5p13.1
Exon count:
43
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (40998020..41071342, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (40998122..41071444, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene caspase recruitment domain family member 6 Neighboring gene RNA, U7 small nuclear 161 pseudogene Neighboring gene complement C7 Neighboring gene uncharacterized LOC105374739 Neighboring gene complement C6 Neighboring gene uncharacterized LOC102723740

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ40243, DKFZp781F0822

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in protein kinase A signaling ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in acrosomal vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in sperm flagellum ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in sperm midpiece ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
maestro heat-like repeat-containing protein family member 2B
Names
HEAT repeat family member 7B2
HEAT repeat family member B2
HEAT repeat-containing protein 7B2
sperm PKA-interacting factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173489.5NP_775760.3  maestro heat-like repeat-containing protein family member 2B

    See identical proteins and their annotated locations for NP_775760.3

    Status: VALIDATED

    Source sequence(s)
    AC114967, AK128183, BC034600, BC044937, BC052962, BF979306, CR749346
    Consensus CDS
    CCDS47202.1
    UniProtKB/Swiss-Prot
    Q7Z745
    UniProtKB/TrEMBL
    B3KXY2, Q4G0Z6
    Related
    ENSP00000382476.4, ENST00000399564.5
    Conserved Domains (1) summary
    sd00044
    Location:13061329
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    40998020..41071342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011513953.1XP_011512255.1  maestro heat-like repeat-containing protein family member 2B isoform X2

    Related
    ENST00000515297.5
    Conserved Domains (1) summary
    sd00044
    Location:12441267
    HEAT; HEAT repeat [structural motif]
  2. XM_011513952.1XP_011512254.1  maestro heat-like repeat-containing protein family member 2B isoform X1

    Conserved Domains (1) summary
    sd00044
    Location:13061329
    HEAT; HEAT repeat [structural motif]
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