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PABPC4L poly(A) binding protein cytoplasmic 4 like [ Homo sapiens (human) ]

Gene ID: 132430, updated on 23-Nov-2021

Summary

Official Symbol
PABPC4Lprovided by HGNC
Official Full Name
poly(A) binding protein cytoplasmic 4 likeprovided by HGNC
Primary source
HGNC:HGNC:31955
See related
Ensembl:ENSG00000254535
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See PABPC4L in Genome Data Viewer
Location:
4q28.3
Exon count:
12
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (133948459..134201789, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (135117488..135122944, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene protocadherin 10 Neighboring gene Sharpr-MPRA regulatory region 13606 Neighboring gene pescadillo ribosomal biogenesis factor 1 pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 2462

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686J06116

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables poly(A) binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables poly(U) RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
polyadenylate-binding protein 4-like
Names
PABP-4-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114734.2NP_001108206.3  polyadenylate-binding protein 4-like

    Status: VALIDATED

    Source sequence(s)
    AC015631, BX648831, DR005318
    Related
    ENSP00000463233.1, ENST00000421491.4
    Conserved Domains (1) summary
    cl25887
    Location:10369
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  2. NM_001363585.1NP_001350514.1  polyadenylate-binding protein 4-like

    Status: VALIDATED

    Source sequence(s)
    AC015631
    Conserved Domains (1) summary
    cl25887
    Location:10369
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    133948459..134201789 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001741135.1 RNA Sequence

  2. XR_001741134.1 RNA Sequence

  3. XR_001741133.1 RNA Sequence

  4. XR_001741139.1 RNA Sequence

  5. XR_001741136.1 RNA Sequence

  6. XR_001741138.1 RNA Sequence

  7. XR_001741137.1 RNA Sequence

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