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OCIAD2 OCIA domain containing 2 [ Homo sapiens (human) ]

Gene ID: 132299, updated on 1-Aug-2020

Summary

Official Symbol
OCIAD2provided by HGNC
Official Full Name
OCIA domain containing 2provided by HGNC
Primary source
HGNC:HGNC:28685
See related
Ensembl:ENSG00000145247
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in kidney (RPKM 105.3), duodenum (RPKM 61.3) and 22 other tissues See more
Orthologs

Genomic context

See OCIAD2 in Genome Data Viewer
Location:
4p11
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (48885019..48906828, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (48887405..48908815, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene FRY like transcription coactivator Neighboring gene RNA, U5E small nuclear 3, pseudogene Neighboring gene OCIAD1 antisense RNA 1 Neighboring gene OCIA domain containing 1 Neighboring gene RNA, U6 small nuclear 158, pseudogene Neighboring gene cell wall biogenesis 43 C-terminal homolog Neighboring gene triosephosphate isomerase 1 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC45416, DKFZp686C03164

Gene Ontology Provided by GOA

Process Evidence Code Pubs
response to bacterium IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
OCIA domain-containing protein 2
Names
ovarian cancer immunoreactive antigen domain containing 2
ovarian carcinoma immunoreactive antigen-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014446.3NP_001014446.1  OCIA domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001014446.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC105444, AK298305
    Consensus CDS
    CCDS33981.1
    UniProtKB/Swiss-Prot
    Q56VL3
    Related
    ENSP00000423014.1, ENST00000508632.6
    Conserved Domains (1) summary
    pfam07051
    Location:15119
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  2. NM_001286773.1NP_001273702.1  OCIA domain-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001273702.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an exon in the central coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.
    Source sequence(s)
    BC032808, BG748993, BI546814, W68799
    Consensus CDS
    CCDS3485.1
    UniProtKB/Swiss-Prot
    Q56VL3
    Related
    ENSP00000483997.1, ENST00000620187.4
    Conserved Domains (1) summary
    pfam07051
    Location:3388
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  3. NM_001286774.1NP_001273703.1  OCIA domain-containing protein 2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in its 5' UTR and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1
    Source sequence(s)
    BG748993, BI546814, BU508058
    Related
    ENST00000508069.6
    Conserved Domains (1) summary
    pfam07051
    Location:157
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  4. NM_152398.3NP_689611.1  OCIA domain-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_689611.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the central coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.
    Source sequence(s)
    BC032808, BG748993, BI546814
    Consensus CDS
    CCDS3485.1
    UniProtKB/Swiss-Prot
    Q56VL3
    Related
    ENSP00000273860.4, ENST00000273860.8
    Conserved Domains (1) summary
    pfam07051
    Location:3388
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)

RNA

  1. NR_104589.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks several internal exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    BG748993, BI546814, BM756234
    Related
    ENST00000506226.6

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    48885019..48906828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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