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SNTN sentan, cilia apical structure protein [ Homo sapiens (human) ]

Gene ID: 132203, updated on 12-Oct-2019

Summary

Official Symbol
SNTNprovided by HGNC
Official Full Name
sentan, cilia apical structure proteinprovided by HGNC
Primary source
HGNC:HGNC:33706
See related
Ensembl:ENSG00000188817 MIM:617832
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
S100AL; sentan; S100A1L
Expression
Restricted expression toward lung (RPKM 7.7) See more
Orthologs

Genomic context

See SNTN in Genome Data Viewer
Location:
3p14.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (63652675..63665212)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (63638344..63650893)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ubiquitin like 5 pseudogene 3 Neighboring gene synaptoporin Neighboring gene SYNPR antisense RNA 1 Neighboring gene RNA, 5S ribosomal pseudogene 134 Neighboring gene VISTA enhancer hs1387 Neighboring gene uncharacterized LOC105377119

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ44379

Gene Ontology Provided by GOA

Function Evidence Code Pubs
transition metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sentan
Names
S100A-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080537.2NP_001074006.1  sentan isoform 2

    See identical proteins and their annotated locations for NP_001074006.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AC136289
    Consensus CDS
    CCDS33779.1
    UniProtKB/Swiss-Prot
    A6NMZ2
    Related
    ENSP00000341442.3, ENST00000343837.8
    Conserved Domains (1) summary
    cd00213
    Location:54138
    S-100; S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 ...
  2. NM_001348756.2NP_001335685.1  sentan isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC136289
    Related
    ENSP00000420078.1, ENST00000469440.5
    Conserved Domains (1) summary
    cd00213
    Location:54168
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    63652675..63665212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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