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Ddost dolichyl-di-phosphooligosaccharide-protein glycotransferase [ Mus musculus (house mouse) ]

Gene ID: 13200, updated on 5-Feb-2023


Official Symbol
Ddostprovided by MGI
Official Full Name
dolichyl-di-phosphooligosaccharide-protein glycotransferaseprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000028757 AllianceGenome:MGI:1194508
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Predicted to enable enzyme activator activity. Predicted to be involved in several processes, including T cell activation; protein N-linked glycosylation via asparagine; and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be part of oligosaccharyltransferase complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ir. Orthologous to human DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in colon adult (RPKM 167.1), ovary adult (RPKM 166.7) and 28 other tissues See more
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Genomic context

See Ddost in Genome Data Viewer
4; 4 D3
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (138032049..138039930)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (138304738..138312619)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 5 Neighboring gene predicted gene, 54278 Neighboring gene kinesin family member 17 Neighboring gene microRNA 7019 Neighboring gene PTEN induced putative kinase 1 Neighboring gene cytidine deaminase

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


GeneRIFs: Gene References Into Functions

What's a GeneRIF?



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 


Products Interactant Other Gene Complex Source Pubs Description

General gene information



Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables enzyme activator activity ISO
Inferred from Sequence Orthology
more info
Process Evidence Code Pubs
involved_in T cell activation ISO
Inferred from Sequence Orthology
more info
involved_in protein N-linked glycosylation ISO
Inferred from Sequence Orthology
more info
involved_in protein N-linked glycosylation via asparagine IBA
Inferred from Biological aspect of Ancestor
more info
involved_in regulation of protein stability ISO
Inferred from Sequence Orthology
more info
involved_in response to cytokine ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
located_in endoplasmic reticulum membrane NAS
Non-traceable Author Statement
more info
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
located_in membrane IEA
Inferred from Electronic Annotation
more info
part_of oligosaccharyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
part_of oligosaccharyltransferase complex ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
DDOST 48 kDa subunit
oligosaccharyl transferase 48 kDa subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007838.3NP_031864.2  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor

    See identical proteins and their annotated locations for NP_031864.2

    Status: VALIDATED

    Source sequence(s)
    BC068132, BU755176
    Consensus CDS
    O54734, Q8C4P7
    ENSMUSP00000030538.5, ENSMUST00000030538.5
    Conserved Domains (1) summary
    DDOST_48kD; Oligosaccharyltransferase 48 kDa subunit beta

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000070.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)