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Vps26c VPS26 endosomal protein sorting factor C [ Mus musculus (house mouse) ]

Gene ID: 13185, updated on 30-Apr-2024

Summary

Official Symbol
Vps26cprovided by MGI
Official Full Name
VPS26 endosomal protein sorting factor Cprovided by MGI
Primary source
MGI:MGI:1206040
See related
Ensembl:ENSMUSG00000022898 AllianceGenome:MGI:1206040
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dcra; Dscr3
Summary
Predicted to be involved in endocytic recycling and intracellular protein transport. Predicted to be active in endosome. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human VPS26C (VPS26 endosomal protein sorting factor C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 34.4), CNS E18 (RPKM 22.7) and 28 other tissues See more
Orthologs
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Genomic context

See Vps26c in Genome Data Viewer
Location:
16 C4; 16 55.23 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (94298583..94327488, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (94497724..94526629, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene developmental pluripotency associated 5 pseudogene Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class P Neighboring gene tetratricopeptide repeat domain 3 Neighboring gene predicted gene, 23692 Neighboring gene predicted gene, 31323 Neighboring gene STARR-positive B cell enhancer ABC_E1498 Neighboring gene STARR-positive B cell enhancer ABC_E9431 Neighboring gene STARR-seq mESC enhancer starr_41576 Neighboring gene STARR-seq mESC enhancer starr_41578 Neighboring gene STARR-positive B cell enhancer ABC_E5566 Neighboring gene dual-specificity tyrosine phosphorylation regulated kinase 1a Neighboring gene STARR-positive B cell enhancer mm9_chr16:94853523-94853824 Neighboring gene predicted gene, 53922 Neighboring gene predicted gene, 41504

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Clone Names

  • MGC5833

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in endocytic recycling ISO
Inferred from Sequence Orthology
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
vacuolar protein sorting-associated protein 26C
Names
DSCR3 arrestin fold containing
Down syndrome critical region gene 3
Down syndrome critical region gene A
Down syndrome critical region protein 3 homolog
Down syndrome critical region protein A homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007834.3NP_031860.1  vacuolar protein sorting-associated protein 26C

    See identical proteins and their annotated locations for NP_031860.1

    Status: VALIDATED

    Source sequence(s)
    AK077628, BU709449, BY483431
    Consensus CDS
    CCDS28349.1
    UniProtKB/Swiss-Prot
    O35075, Q542V5
    Related
    ENSMUSP00000023615.7, ENSMUST00000023615.7
    Conserved Domains (1) summary
    cl22903
    Location:1283
    Arrestin_N; Arrestin (or S-antigen), N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    94298583..94327488 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)