Format

Send to:

Choose Destination

ERICH6 glutamate rich 6 [ Homo sapiens (human) ]

Gene ID: 131831, updated on 23-Nov-2021

Summary

Official Symbol
ERICH6provided by HGNC
Official Full Name
glutamate rich 6provided by HGNC
Primary source
HGNC:HGNC:28602
See related
Ensembl:ENSG00000163645
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C3orf44; ERICH6A; FAM194A
Expression
Restricted expression toward testis (RPKM 13.0) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ERICH6 in Genome Data Viewer
Location:
3q25.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (150659885..150704563, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (150377672..150421707, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene selenoprotein T Neighboring gene Sin3A associated protein 30kDa pseudogene Neighboring gene Sharpr-MPRA regulatory region 4372 Neighboring gene ERICH6 antisense RNA 1 Neighboring gene CRISPRi-validated cis-regulatory element chr3.4443 Neighboring gene small nuclear ribonucleoprotein polypeptide C pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC39662

General protein information

Preferred Names
glutamate-rich protein 6
Names
family with sequence similarity 194, member A
glutamate-rich 6A
protein FAM194A

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308234.2NP_001295163.1  glutamate-rich protein 6 isoform 2

    See identical proteins and their annotated locations for NP_001295163.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' terminal exon compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG to encode an isoform (2) that has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC011317, BC029577
    Consensus CDS
    CCDS77840.1
    UniProtKB/Swiss-Prot
    Q7L0X2
    Related
    ENSP00000419366.1, ENST00000491361.5
    Conserved Domains (1) summary
    pfam14977
    Location:276473
    FAM194; FAM194 protein
  2. NM_152394.5NP_689607.2  glutamate-rich protein 6 isoform 1

    See identical proteins and their annotated locations for NP_689607.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC029577, BC036239, DB058602
    Consensus CDS
    CCDS3151.2
    UniProtKB/Swiss-Prot
    Q7L0X2
    Related
    ENSP00000295910.6, ENST00000295910.11
    Conserved Domains (1) summary
    pfam14977
    Location:422619
    FAM194; FAM194 protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    150659885..150704563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005247120.3XP_005247177.1  glutamate-rich protein 6 isoform X1

    Conserved Domains (1) summary
    pfam14977
    Location:422499
    FAM194; FAM194 protein
Support Center