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TMEM42 transmembrane protein 42 [ Homo sapiens (human) ]

Gene ID: 131616, updated on 11-Jun-2021

Summary

Official Symbol
TMEM42provided by HGNC
Official Full Name
transmembrane protein 42provided by HGNC
Primary source
HGNC:HGNC:28444
See related
Ensembl:ENSG00000169964
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in testis (RPKM 12.3), thyroid (RPKM 8.6) and 25 other tissues See more
Orthologs
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Genomic context

See TMEM42 in Genome Data Viewer
Location:
3p21.31
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (44861912..44865664)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (44903404..44907156)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene KIAA1143 Neighboring gene kinesin family member 15 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 77 Neighboring gene microRNA 564 Neighboring gene peptidylprolyl isomerase A pseudogene 18 Neighboring gene Sharpr-MPRA regulatory region 3821 Neighboring gene transglutaminase 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC29956

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144638.3NP_653239.1  transmembrane protein 42

    See identical proteins and their annotated locations for NP_653239.1

    Status: VALIDATED

    Source sequence(s)
    AL532443, BC019851, DB499198
    Consensus CDS
    CCDS2722.1
    UniProtKB/Swiss-Prot
    Q69YG0
    Related
    ENSP00000306564.4, ENST00000302392.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    44861912..44865664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_009646197.1 Reference GRCh38.p13 PATCHES

    Range
    387262..391014
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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