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Dab1 disabled 1 [ Mus musculus (house mouse) ]

Gene ID: 13131, updated on 10-Jan-2023

Summary

Official Symbol
Dab1provided by MGI
Official Full Name
disabled 1provided by MGI
Primary source
MGI:MGI:108554
See related
Ensembl:ENSMUSG00000028519 AllianceGenome:MGI:108554
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
scm; scr; yot; scrambler; C630028C02Rik
Summary
Predicted to enable phosphatidylinositol 3-kinase binding activity. Involved in lateral motor column neuron migration. Acts upstream of or within several processes, including adult walking behavior; negative regulation of receptor signaling pathway via JAK-STAT; and nervous system development. Located in perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Orthologous to human DAB1 (DAB adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 14.1), whole brain E14.5 (RPKM 10.9) and 11 other tissues See more
Orthologs
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Genomic context

See Dab1 in Genome Data Viewer
Location:
4 C6; 4 47.79 cM
Exon count:
31
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (103476425..104602041)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (103619500..104744844)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene actin, gamma, cytoplasmic 1 pseudogene Neighboring gene predicted gene, 25877 Neighboring gene predicted gene, 36604 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 36661 Neighboring gene complement component 8, beta polypeptide Neighboring gene complement component 8, alpha polypeptide Neighboring gene FYN binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SH2 domain binding TAS
Traceable Author Statement
more info
PubMed 
enables phosphatidylinositol 3-kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables phospholipid binding TAS
Traceable Author Statement
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within Golgi localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within adult walking behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of astrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of axonogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in central nervous system development TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within cerebellum structural organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cerebral cortex cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cerebral cortex radially oriented cell migration IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within cerebral cortex radially oriented cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cerebral cortex radially oriented cell migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within dendrite development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within dendrite development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within hippocampus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular signal transduction TAS
Traceable Author Statement
more info
PubMed 
involved_in lateral motor column neuron migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in lateral motor column neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within motor neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of astrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of axonogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within negative regulation of axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of receptor signaling pathway via JAK-STAT IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in nervous system development NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuron migration IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuron migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of protein kinase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within radial glia guided migration of Purkinje cell IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within radial glia guided migration of Purkinje cell IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within radial glia-guided pyramidal neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of receptor signaling pathway via JAK-STAT IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within small GTPase mediated signal transduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ventral spinal cord development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ventral spinal cord development IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in apical part of cell ISO
Inferred from Sequence Orthology
more info
 
located_in brush border ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm IGI
Inferred from Genetic Interaction
more info
PubMed 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
disabled homolog 1
Names
yotari

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001369046.1NP_001355975.1  disabled homolog 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variants 2 and 5, encodes isoform 2.
    Source sequence(s)
    AL626762, AL627134, AL645483, AL645666, AL669938, AL772211
    Consensus CDS
    CCDS18413.1
    UniProtKB/TrEMBL
    A0A6P5PQF7, B2RRQ8
    Conserved Domains (2) summary
    PRK07764
    Location:255436
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  2. NM_001369047.1NP_001355976.1  disabled homolog 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 2 and 4, encodes isoform 2.
    Source sequence(s)
    AL626762, AL627134, AL645483, AL645666, AL669938, AL772211
    Consensus CDS
    CCDS18413.1
    UniProtKB/TrEMBL
    A0A6P5PQF7, B2RRQ8
    Conserved Domains (2) summary
    PRK07764
    Location:255436
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  3. NM_001369048.1NP_001355977.1  disabled homolog 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL626762, AL627134, AL645483, AL645666, AL669938, AL772211
    Consensus CDS
    CCDS89790.1
    UniProtKB/TrEMBL
    A0A8C6GTH6
    Related
    ENSMUSP00000102440.2, ENSMUST00000106827.8
    Conserved Domains (1) summary
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  4. NM_001369049.1NP_001355978.1  disabled homolog 1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) encodes the longest isoform (4).
    Source sequence(s)
    AL626762, AL627134, AL645483, AL645666, AL669938, AL772211
    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  5. NM_010014.3NP_034144.1  disabled homolog 1 isoform 1

    See identical proteins and their annotated locations for NP_034144.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) lacks several exons and includes an alternate 3' terminal exon, compared to variant 2. It encodes isoform 1 which is shorter and has a distinct C-terminus, compared to isoform 2.
    Source sequence(s)
    BE947086, BY264959, Y08381
    UniProtKB/Swiss-Prot
    P97318
    Related
    ENSMUSP00000102439.2, ENSMUST00000106826.8
    Conserved Domains (1) summary
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  6. NM_177259.4NP_796233.2  disabled homolog 1 isoform 2

    See identical proteins and their annotated locations for NP_796233.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variants 4 and 5, encodes isoform 2.
    Source sequence(s)
    AK045616, BC138538, BE945099, BY264959, Y08379
    Consensus CDS
    CCDS18413.1
    UniProtKB/Swiss-Prot
    P97318
    UniProtKB/TrEMBL
    A0A6P5PQF7, B2RRQ8
    Related
    ENSMUSP00000102443.3, ENSMUST00000106830.9
    Conserved Domains (2) summary
    PRK07764
    Location:255436
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain

RNA

  1. NR_104385.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate internal exon, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AL627134, AL645483, AL669938

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    103476425..104602041
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163642.1XP_036019535.1  disabled homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A6P7R5Y7
    Conserved Domains (2) summary
    PRK07764
    Location:253434
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  2. XM_036163645.1XP_036019538.1  disabled homolog 1 isoform X15

    UniProtKB/TrEMBL
    A0A8C6GTH6
    Conserved Domains (1) summary
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  3. XM_006502725.5XP_006502788.1  disabled homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_006502788.1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  4. XM_036163638.1XP_036019531.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  5. XM_036163640.1XP_036019533.1  disabled homolog 1 isoform X4

    UniProtKB/TrEMBL
    A0A6P5PQF7, B2RRQ8
    Conserved Domains (2) summary
    PRK07764
    Location:255436
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  6. XM_036163635.1XP_036019528.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  7. XM_011240426.3XP_011238728.1  disabled homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_011238728.1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  8. XM_036163636.1XP_036019529.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  9. XM_030253166.2XP_030109026.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  10. XM_036163637.1XP_036019530.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  11. XM_036163641.1XP_036019534.1  disabled homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A6P7R5Y7
    Conserved Domains (2) summary
    PRK07764
    Location:253434
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  12. XM_036163633.1XP_036019526.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  13. XM_036163632.1XP_036019525.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  14. XM_030253165.2XP_030109025.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  15. XM_017319948.2XP_017175437.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  16. XM_030253172.2XP_030109032.1  disabled homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A6P7R5Y7
    Conserved Domains (2) summary
    PRK07764
    Location:253434
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  17. XM_006502727.5XP_006502790.1  disabled homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_006502790.1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  18. XM_030253170.2XP_030109030.1  disabled homolog 1 isoform X4

    UniProtKB/TrEMBL
    A0A6P5PQF7, B2RRQ8
    Conserved Domains (2) summary
    PRK07764
    Location:255436
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  19. XM_030253175.2XP_030109035.1  disabled homolog 1 isoform X8

    Conserved Domains (2) summary
    PHA03247
    Location:254434
    PHA03247; large tegument protein UL36; Provisional
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  20. XM_030253182.2XP_030109042.1  disabled homolog 1 isoform X15

    UniProtKB/TrEMBL
    A0A8C6GTH6
    Conserved Domains (1) summary
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  21. XM_036163643.1XP_036019536.1  disabled homolog 1 isoform X12

    Conserved Domains (2) summary
    PRK07764
    Location:220401
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  22. XM_036163644.1XP_036019537.1  disabled homolog 1 isoform X14

    Conserved Domains (2) summary
    PRK07764
    Location:220401
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  23. XM_030253180.2XP_030109040.1  disabled homolog 1 isoform X15

    UniProtKB/TrEMBL
    A0A8C6GTH6
    Conserved Domains (1) summary
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  24. XM_030253169.2XP_030109029.1  disabled homolog 1 isoform X3

    UniProtKB/TrEMBL
    A0A6P7QVA6
    Conserved Domains (2) summary
    PHA03247
    Location:287467
    PHA03247; large tegument protein UL36; Provisional
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  25. XM_030253177.2XP_030109037.1  disabled homolog 1 isoform X10

    Conserved Domains (2) summary
    PRK07764
    Location:253434
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  26. XM_006502726.2XP_006502789.1  disabled homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_006502789.1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  27. XM_030253174.1XP_030109034.1  disabled homolog 1 isoform X7

    Conserved Domains (2) summary
    PRK07764
    Location:251432
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  28. XM_030253167.2XP_030109027.1  disabled homolog 1 isoform X2

    Conserved Domains (2) summary
    PRK07764
    Location:286467
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  29. XM_030253173.2XP_030109033.1  disabled homolog 1 isoform X6

    Conserved Domains (2) summary
    PRK07764
    Location:253434
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  30. XM_030253171.1XP_030109031.1  disabled homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A6P7R5Y7
    Conserved Domains (2) summary
    PRK07764
    Location:253434
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  31. XM_017319950.3XP_017175439.1  disabled homolog 1 isoform X8

    Conserved Domains (2) summary
    PHA03247
    Location:254434
    PHA03247; large tegument protein UL36; Provisional
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  32. XM_030253176.2XP_030109036.1  disabled homolog 1 isoform X9

    Conserved Domains (2) summary
    PHA03247
    Location:252432
    PHA03247; large tegument protein UL36; Provisional
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  33. XM_030253178.1XP_030109038.1  disabled homolog 1 isoform X12

    Conserved Domains (2) summary
    PRK07764
    Location:220401
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  34. XM_030253179.2XP_030109039.1  disabled homolog 1 isoform X13

    Conserved Domains (2) summary
    PRK07764
    Location:218399
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  35. XM_036163639.1XP_036019532.1  disabled homolog 1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:288469
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01215
    Location:25174
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
  36. XM_006502735.3XP_006502798.1  disabled homolog 1 isoform X11

    Conserved Domains (2) summary
    PRK07764
    Location:224405
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cl17171
    Location:1110
    PH-like; Pleckstrin homology-like domain