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OSR1 odd-skipped related transcription factor 1 [ Homo sapiens (human) ]

Gene ID: 130497, updated on 11-Jun-2021

Summary

Official Symbol
OSR1provided by HGNC
Official Full Name
odd-skipped related transcription factor 1provided by HGNC
Primary source
HGNC:HGNC:8111
See related
Ensembl:ENSG00000143867 MIM:608891
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ODD
Annotation information
Note: OSR1 (Gene ID: 130497) and OXSR1 (Gene ID: 9943) share the OSR1 symbol/alias in common. OSR1 is a widely used alternative name for oxidative stress responsive 1 (OXSR1). [29 Jun 2018]
Expression
Broad expression in salivary gland (RPKM 5.4), endometrium (RPKM 5.3) and 19 other tissues See more
Orthologs
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Genomic context

See OSR1 in Genome Data Viewer
Location:
2p24.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (19351485..19358623, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (19551246..19558384, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373455 Neighboring gene microRNA 4757 Neighboring gene uncharacterized LOC101928196 Neighboring gene uncharacterized LOC105373458 Neighboring gene long intergenic non-protein coding RNA 1808

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cell proliferation involved in kidney development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to retinoic acid IEA
Inferred from Electronic Annotation
more info
 
involved_in chondrocyte differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in embryo development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in embryonic digit morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in embryonic forelimb morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in embryonic hindlimb morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in embryonic skeletal joint development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in embryonic skeletal joint morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in embryonic skeletal limb joint morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in gonad development IEA
Inferred from Electronic Annotation
more info
 
involved_in heart development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in intermediate mesoderm development IEA
Inferred from Electronic Annotation
more info
 
involved_in mesangial cell development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in mesonephric duct morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in mesonephros development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric cap mesenchymal cell proliferation involved in metanephros development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric epithelium development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric glomerulus vasculature development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric interstitial fibroblast development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric mesenchymal cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric mesenchyme development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric mesenchyme morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric nephron tubule development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in metanephric smooth muscle tissue development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in middle ear morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of creatine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 
involved_in negative regulation of epithelial cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of nephron tubule epithelial cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of sodium ion transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in odontogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in pattern specification involved in metanephros development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of bone mineralization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of epithelial cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of gastrulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in posterior mesonephric tubule development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in pronephros development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in renal vesicle progenitor cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in roof of mouth development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in specification of anterior mesonephric tubule identity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in specification of posterior mesonephric tubule identity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in stem cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in ureter urothelium development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in ureteric bud development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in urogenital system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in urogenital system development ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in extrinsic component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
protein odd-skipped-related 1
Names
odd-skipped homolog
odd-skipped related 1
odd-skipped related transciption factor 1
NP_660303.1
XP_006712005.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145260.3NP_660303.1  protein odd-skipped-related 1

    See identical proteins and their annotated locations for NP_660303.1

    Status: VALIDATED

    Source sequence(s)
    AC018741, AI391506, AK074591
    Consensus CDS
    CCDS1694.1
    UniProtKB/Swiss-Prot
    Q8TAX0
    Related
    ENSP00000272223.2, ENST00000272223.3
    Conserved Domains (3) summary
    sd00017
    Location:177197
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:175197
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:217240
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    19351485..19358623 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006711942.4XP_006712005.1  protein odd-skipped-related 1 isoform X1

    See identical proteins and their annotated locations for XP_006712005.1

    UniProtKB/Swiss-Prot
    Q8TAX0
    Conserved Domains (3) summary
    sd00017
    Location:177197
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:175197
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:217240
    zf-H2C2_2; Zinc-finger double domain
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