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OR9A4 olfactory receptor family 9 subfamily A member 4 [ Homo sapiens (human) ]

Gene ID: 130075, updated on 22-Sep-2022

Summary

Official Symbol
OR9A4provided by HGNC
Official Full Name
olfactory receptor family 9 subfamily A member 4provided by HGNC
Primary source
HGNC:HGNC:15095
See related
Ensembl:ENSG00000258083 AllianceGenome:HGNC:15095
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR9A4 in Genome Data Viewer
Location:
7q34
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (141916399..141920625)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (143232170..143236396)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (141616199..141620425)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 9 subfamily A member 1 pseudogene Neighboring gene olfactory receptor family 9 subfamily N member 1 pseudogene Neighboring gene uncharacterized LOC124901761 Neighboring gene C-type lectin domain containing 5A Neighboring gene taste 2 receptor member 38

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 9A4
Names
olfactory receptor OR7-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001656.3NP_001001656.1  olfactory receptor 9A4

    See identical proteins and their annotated locations for NP_001001656.1

    Status: VALIDATED

    Source sequence(s)
    AC073647
    Consensus CDS
    CCDS43661.1
    UniProtKB/Swiss-Prot
    Q6IFI4, Q8NGU2
    UniProtKB/TrEMBL
    A0A126GVB1
    Related
    ENSP00000493151.1, ENST00000641559.1
    Conserved Domains (2) summary
    pfam00001
    Location:40289
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:30307
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    141916399..141920625
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    143232170..143236396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)