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FAM168B family with sequence similarity 168 member B [ Homo sapiens (human) ]

Gene ID: 130074, updated on 6-May-2021

Summary

Official Symbol
FAM168Bprovided by HGNC
Official Full Name
family with sequence similarity 168 member Bprovided by HGNC
Primary source
HGNC:HGNC:27016
See related
Ensembl:ENSG00000152102
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MANI
Expression
Ubiquitous expression in brain (RPKM 37.0), fat (RPKM 23.7) and 25 other tissues See more
Orthologs
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Genomic context

See FAM168B in Genome Data Viewer
Location:
2q21.1
Exon count:
12
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (131047876..131093468, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (131805449..131851033, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene APC membrane recruitment protein 3 Neighboring gene CYCS pseudogene 8 Neighboring gene Rho guanine nucleotide exchange factor 4 Neighboring gene pleckstrin homology domain containing B2 Neighboring gene NEK2 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC87527

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular exosome HDA PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
myelin-associated neurite-outgrowth inhibitor
Names
protein FAM168B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009993.4NP_001009993.2  myelin-associated neurite-outgrowth inhibitor

    See identical proteins and their annotated locations for NP_001009993.2

    Status: VALIDATED

    Source sequence(s)
    BC110642, CN418443, DB453209
    Consensus CDS
    CCDS42755.1
    UniProtKB/Swiss-Prot
    A1KXE4
    UniProtKB/TrEMBL
    A0A024QZ31
    Related
    ENSP00000374565.3, ENST00000389915.4
    Conserved Domains (1) summary
    pfam14944
    Location:1195
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
  2. NM_001321743.1NP_001308672.1  myelin-associated neurite-outgrowth inhibitor

    Status: VALIDATED

    Source sequence(s)
    AC009477
    Consensus CDS
    CCDS42755.1
    UniProtKB/Swiss-Prot
    A1KXE4
    UniProtKB/TrEMBL
    A0A024QZ31
    Conserved Domains (1) summary
    pfam14944
    Location:1195
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
  3. NM_001321744.1NP_001308673.1  myelin-associated neurite-outgrowth inhibitor

    Status: VALIDATED

    Source sequence(s)
    AC009477
    Consensus CDS
    CCDS42755.1
    UniProtKB/Swiss-Prot
    A1KXE4
    UniProtKB/TrEMBL
    A0A024QZ31
    Conserved Domains (1) summary
    pfam14944
    Location:1195
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
  4. NM_001321745.1NP_001308674.1  myelin-associated neurite-outgrowth inhibitor

    Status: VALIDATED

    Source sequence(s)
    AC009477
    Consensus CDS
    CCDS42755.1
    UniProtKB/Swiss-Prot
    A1KXE4
    UniProtKB/TrEMBL
    A0A024QZ31
    Conserved Domains (1) summary
    pfam14944
    Location:1195
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
  5. NM_001321746.2NP_001308675.1  myelin-associated neurite-outgrowth inhibitor

    Status: VALIDATED

    Source sequence(s)
    AC009477, BC110642, CN418443
    Consensus CDS
    CCDS42755.1
    UniProtKB/Swiss-Prot
    A1KXE4
    UniProtKB/TrEMBL
    A0A024QZ31
    Related
    ENSP00000387051.1, ENST00000409185.5
    Conserved Domains (1) summary
    pfam14944
    Location:1195
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
  6. NM_001321747.2NP_001308676.1  myelin-associated neurite-outgrowth inhibitor

    Status: VALIDATED

    Source sequence(s)
    AC009477
    Consensus CDS
    CCDS42755.1
    UniProtKB/Swiss-Prot
    A1KXE4
    UniProtKB/TrEMBL
    A0A024QZ31
    Conserved Domains (1) summary
    pfam14944
    Location:1195
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
  7. NM_001321748.2NP_001308677.1  myelin-associated neurite-outgrowth inhibitor

    Status: VALIDATED

    Source sequence(s)
    AC009477
    Consensus CDS
    CCDS42755.1
    UniProtKB/Swiss-Prot
    A1KXE4
    UniProtKB/TrEMBL
    A0A024QZ31
    Conserved Domains (1) summary
    pfam14944
    Location:1195
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    131047876..131093468 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017003328.1XP_016858817.1  myelin-associated neurite-outgrowth inhibitor isoform X2

    Conserved Domains (1) summary
    pfam14944
    Location:24168
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
  2. XM_017003327.1XP_016858816.1  myelin-associated neurite-outgrowth inhibitor isoform X1

    UniProtKB/Swiss-Prot
    A1KXE4
    UniProtKB/TrEMBL
    A0A024QZ31
    Conserved Domains (1) summary
    pfam14944
    Location:1195
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
  3. XM_011510594.3XP_011508896.1  myelin-associated neurite-outgrowth inhibitor isoform X2

    See identical proteins and their annotated locations for XP_011508896.1

    Conserved Domains (1) summary
    pfam14944
    Location:24168
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
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