Format

Send to:

Choose Destination

Csf3 colony stimulating factor 3 (granulocyte) [ Mus musculus (house mouse) ]

Gene ID: 12985, updated on 5-Dec-2021

Summary

Official Symbol
Csf3provided by MGI
Official Full Name
colony stimulating factor 3 (granulocyte)provided by MGI
Primary source
MGI:MGI:1339751
See related
Ensembl:ENSMUSG00000038067
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Csfg; G-CSF; MGI-IG
Expression
Biased expression in ovary adult (RPKM 3.1), genital fat pad adult (RPKM 0.7) and 4 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Csf3 in Genome Data Viewer
Location:
11 D; 11 62.45 cM
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (98591287..98594457)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (98700183..98703631)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (98562627..98564943)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene gasdermin A Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 Neighboring gene predicted gene, 38985 Neighboring gene mediator complex subunit 24 Neighboring gene predicted gene, 22059 Neighboring gene predicted gene, 31252

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cytokine activity ISO
Inferred from Sequence Orthology
more info
 
enables cytokine activity NAS
Non-traceable Author Statement
more info
PubMed 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables granulocyte colony-stimulating factor receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables granulocyte colony-stimulating factor receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables growth factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to cytokine stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in granulocyte differentiation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of actin cytoskeleton reorganization ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of actin filament polymerization ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of myeloid cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within positive regulation of myeloid cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of peptidyl-serine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of phosphatidylinositol 3-kinase signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein binding ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein kinase B signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endocytic vesicle lumen TAS
Traceable Author Statement
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region TAS
Traceable Author Statement
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
granulocyte colony-stimulating factor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009971.1NP_034101.1  granulocyte colony-stimulating factor precursor

    See identical proteins and their annotated locations for NP_034101.1

    Status: VALIDATED

    Source sequence(s)
    M13926
    Consensus CDS
    CCDS25360.1
    UniProtKB/Swiss-Prot
    P09920
    UniProtKB/TrEMBL
    Q0VB73
    Related
    ENSMUSP00000037762.3, ENSMUST00000038886.3
    Conserved Domains (1) summary
    pfam16647
    Location:57205
    GCSF; Granulocyte colony-stimulating factor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    98591287..98594457
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245517.2XP_030101377.1  granulocyte colony-stimulating factor isoform X2

    Conserved Domains (1) summary
    pfam16647
    Location:108256
    GCSF; Granulocyte colony-stimulating factor
  2. XM_006532128.5XP_006532191.3  granulocyte colony-stimulating factor isoform X1

    Conserved Domains (1) summary
    pfam16647
    Location:241389
    GCSF; Granulocyte colony-stimulating factor
Support Center