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Cox7a2 cytochrome c oxidase subunit 7A2 [ Mus musculus (house mouse) ]

Gene ID: 12866, updated on 18-Apr-2024

Summary

Official Symbol
Cox7a2provided by MGI
Official Full Name
cytochrome c oxidase subunit 7A2provided by MGI
Primary source
MGI:MGI:1316715
See related
Ensembl:ENSMUSG00000032330 AllianceGenome:MGI:1316715
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
COX7AL; Cox7a3; CoxVIIa-L
Summary
Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in mitochondrial respirasome assembly and regulation of oxidative phosphorylation. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; heart; hemolymphoid system; integumental system; and nervous system. Orthologous to several human genes including COX7A2 (cytochrome c oxidase subunit 7A2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 183.5), kidney adult (RPKM 165.8) and 28 other tissues See more
Orthologs
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Genomic context

Location:
9 E1; 9 43.82 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (79662523..79667135, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (79755241..79771422, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene 8125 Neighboring gene STARR-seq mESC enhancer starr_24746 Neighboring gene collagen, type XII, alpha 1 Neighboring gene STARR-seq mESC enhancer starr_24747 Neighboring gene STARR-positive B cell enhancer ABC_E2297 Neighboring gene predicted gene, 51685 Neighboring gene RIKEN cDNA 4930429F24 gene Neighboring gene STARR-positive B cell enhancer ABC_E5090 Neighboring gene transmembrane protein 30A Neighboring gene filamin A interacting protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
cytochrome c oxidase subunit 7A2, mitochondrial
Names
cytochrome c oxidase subunit VIIa 2
cytochrome c oxidase subunit VIIa 3
cytochrome c oxidase subunit VIIa-L
cytochrome c oxidase subunit VIIa-liver/heart
NP_034075.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009945.3NP_034075.2  cytochrome c oxidase subunit 7A2, mitochondrial precursor

    See identical proteins and their annotated locations for NP_034075.2

    Status: VALIDATED

    Source sequence(s)
    CN670202, CN838002
    Consensus CDS
    CCDS23366.1
    UniProtKB/Swiss-Prot
    O54969, P48771, Q545J7
    Related
    ENSMUSP00000034881.7, ENSMUST00000034881.8
    Conserved Domains (1) summary
    cd00928
    Location:2478
    Cyt_c_Oxidase_VIIa; Cytochrome c oxidase subunit VIIa. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    79662523..79667135 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)