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C1orf162 chromosome 1 open reading frame 162 [ Homo sapiens (human) ]

Gene ID: 128346, updated on 22-Sep-2022

Summary

Official Symbol
C1orf162provided by HGNC
Official Full Name
chromosome 1 open reading frame 162provided by HGNC
Primary source
HGNC:HGNC:28344
See related
Ensembl:ENSG00000143110 AllianceGenome:HGNC:28344
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in spleen (RPKM 7.0), appendix (RPKM 5.5) and 24 other tissues See more
Orthologs
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Genomic context

See C1orf162 in Genome Data Viewer
Location:
1p13.2
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (111473984..111478512)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (111488667..111493194)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (112016606..112021134)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene WD repeat domain 77 Neighboring gene ATP synthase peripheral stalk-membrane subunit b Neighboring gene transmembrane and immunoglobulin domain containing 3 Neighboring gene RNA, U6 small nuclear 792, pseudogene Neighboring gene adenosine A3 receptor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC24133

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein C1orf162

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001300834.2NP_001287763.1  transmembrane protein C1orf162 isoform 2

    See identical proteins and their annotated locations for NP_001287763.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    BG545926, CA439311
    Consensus CDS
    CCDS72837.1
    UniProtKB/Swiss-Prot
    Q8NEQ5
    Related
    ENSP00000358732.3, ENST00000369718.4
    Conserved Domains (2) summary
    pfam15179
    Location:2162
    Myc_target_1; Myc target protein 1
    cl27601
    Location:46100
    Pectinesterase; Pectinesterase
  2. NM_001300835.2NP_001287764.1  transmembrane protein C1orf162 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
    Source sequence(s)
    AA333542, CA439311, HX785231
  3. NM_174896.4NP_777556.1  transmembrane protein C1orf162 isoform 1

    See identical proteins and their annotated locations for NP_777556.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    BC017973, CA439311
    Consensus CDS
    CCDS837.1
    UniProtKB/Swiss-Prot
    Q5QNZ1, Q8NEQ5
    Related
    ENSP00000344218.5, ENST00000343534.9
    Conserved Domains (1) summary
    pfam15179
    Location:2197
    Myc_target_1; Myc target protein 1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    111473984..111478512
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047446258.1XP_047302214.1  transmembrane protein C1orf162 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    111488667..111493194
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)