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Col19a1 collagen, type XIX, alpha 1 [ Mus musculus (house mouse) ]

Gene ID: 12823, updated on 26-Sep-2022

Summary

Official Symbol
Col19a1provided by MGI
Official Full Name
collagen, type XIX, alpha 1provided by MGI
Primary source
MGI:MGI:1095415
See related
Ensembl:ENSMUSG00000026141 AllianceGenome:MGI:1095415
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be an extracellular matrix structural constituent. Acts upstream of or within extracellular matrix organization and skeletal muscle tissue development. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including bone; brain; genital tubercle; musculature; and sensory organ. Orthologous to human COL19A1 (collagen type XIX alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 2.9), frontal lobe adult (RPKM 2.4) and 6 other tissues See more
Orthologs
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Genomic context

See Col19a1 in Genome Data Viewer
Location:
1; 1 A5
Exon count:
51
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (24296764..24627870, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (24257683..24587922, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 135, member A Neighboring gene predicted gene, 30756 Neighboring gene collagen, type IX, alpha 1 Neighboring gene predicted gene, 26418 Neighboring gene tubulin, beta 4B class IVB, pseudogene 2 Neighboring gene predicted gene 10222

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables extracellular matrix structural constituent IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
collagen alpha-1(XIX) chain
Names
collagen alpha-1(Y) chain
procollagen, type XIX, alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007733.2NP_031759.2  collagen alpha-1(XIX) chain precursor

    See identical proteins and their annotated locations for NP_031759.2

    Status: VALIDATED

    Source sequence(s)
    AC130201, AC153653, AK019854, AK149136, BC118970, BY247446
    Consensus CDS
    CCDS14854.1
    UniProtKB/Swiss-Prot
    O35053, Q0VF58
    Related
    ENSMUSP00000110899.3, ENSMUST00000115244.9
    Conserved Domains (2) summary
    pfam01391
    Location:519576
    Collagen; Collagen triple helix repeat (20 copies)
    smart00210
    Location:50229
    TSPN; Thrombospondin N-terminal -like domains

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    24296764..24627870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006495645.5XP_006495708.1  collagen alpha-1(XIX) chain isoform X4

    See identical proteins and their annotated locations for XP_006495708.1

    UniProtKB/Swiss-Prot
    O35053, Q0VF58
    Conserved Domains (2) summary
    pfam01391
    Location:519576
    Collagen; Collagen triple helix repeat (20 copies)
    smart00210
    Location:50229
    TSPN; Thrombospondin N-terminal -like domains
  2. XM_030245411.2XP_030101271.1  collagen alpha-1(XIX) chain isoform X6

    Conserved Domains (2) summary
    pfam01391
    Location:515572
    Collagen; Collagen triple helix repeat (20 copies)
    smart00210
    Location:76255
    TSPN; Thrombospondin N-terminal -like domains
  3. XM_006495646.5XP_006495709.1  collagen alpha-1(XIX) chain isoform X5

    Conserved Domains (2) summary
    pfam01391
    Location:515572
    Collagen; Collagen triple helix repeat (20 copies)
    smart00210
    Location:76255
    TSPN; Thrombospondin N-terminal -like domains
  4. XM_006495644.5XP_006495707.1  collagen alpha-1(XIX) chain isoform X3

    Conserved Domains (2) summary
    pfam01391
    Location:527584
    Collagen; Collagen triple helix repeat (20 copies)
    smart00210
    Location:76255
    TSPN; Thrombospondin N-terminal -like domains
  5. XM_006495643.5XP_006495706.1  collagen alpha-1(XIX) chain isoform X2

    Conserved Domains (2) summary
    pfam01391
    Location:545602
    Collagen; Collagen triple helix repeat (20 copies)
    smart00210
    Location:76255
    TSPN; Thrombospondin N-terminal -like domains
  6. XM_006495642.5XP_006495705.1  collagen alpha-1(XIX) chain isoform X1

    Conserved Domains (2) summary
    pfam01391
    Location:545602
    Collagen; Collagen triple helix repeat (20 copies)
    smart00210
    Location:76255
    TSPN; Thrombospondin N-terminal -like domains