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LIX1L limb and CNS expressed 1 like [ Homo sapiens (human) ]

Gene ID: 128077, updated on 17-Sep-2024

Summary

Official Symbol
LIX1Lprovided by HGNC
Official Full Name
limb and CNS expressed 1 likeprovided by HGNC
Primary source
HGNC:HGNC:28715
See related
Ensembl:ENSG00000271601 AllianceGenome:HGNC:28715
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in autophagosome maturation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary (RPKM 17.6), endometrium (RPKM 13.1) and 24 other tissues See more
Orthologs
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Genomic context

See LIX1L in Genome Data Viewer
Location:
1q21.1
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (145933423..145958017, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (145050242..145074834, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (145477069..145501670)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 11 beta Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145516673-145517219 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:145516125-145516672 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1616 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1617 Neighboring gene gonadotropin releasing hormone receptor 2 (pseudogene) Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:145507474-145508673 Neighboring gene RNA binding motif protein 8A Neighboring gene LIX1L antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1269 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1270 Neighboring gene conserved acetylation island sequence C12 enhancer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145473321-145474156 Neighboring gene ankyrin repeat domain 34A Neighboring gene Sharpr-MPRA regulatory region 4010 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1621 Neighboring gene RNA polymerase III subunit GL Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145458517-145459016 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1622 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:145455010-145456209

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC46719, DKFZp762F237

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in autophagosome maturation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
LIX1-like protein
Names
Lix1 homolog-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153713.3NP_714924.1  LIX1-like protein

    See identical proteins and their annotated locations for NP_714924.1

    Status: VALIDATED

    Source sequence(s)
    AC243547, AK128733, BC035727
    Consensus CDS
    CCDS72873.1
    UniProtKB/Swiss-Prot
    Q6AI36, Q8IVB5
    UniProtKB/TrEMBL
    B3KY58
    Related
    ENSP00000474487.3, ENST00000604000.4
    Conserved Domains (1) summary
    pfam14954
    Location:87328
    LIX1; Limb expression 1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    145933423..145958017 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    145050242..145074834 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)