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WDR64 WD repeat domain 64 [ Homo sapiens (human) ]

Gene ID: 128025, updated on 5-Feb-2023

Summary

Official Symbol
WDR64provided by HGNC
Official Full Name
WD repeat domain 64provided by HGNC
Primary source
HGNC:HGNC:26570
See related
Ensembl:ENSG00000162843 AllianceGenome:HGNC:26570
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 1.6) and placenta (RPKM 0.1) See more
Orthologs
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Genomic context

See WDR64 in Genome Data Viewer
Location:
1q43
Exon count:
31
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (241652281..241802777)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (241063753..241214784)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (241815583..241966079)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene kynurenine 3-monooxygenase Neighboring gene opsin 3 Neighboring gene CHM like Rab escort protein Neighboring gene uncharacterized LOC124904603 Neighboring gene CRISPRi-validated cis-regulatory element chr1.12743 Neighboring gene uncharacterized LOC105373231

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
A genome-wide association study of behavioral disinhibition.
EBI GWAS Catalog
Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32978

General protein information

Preferred Names
WD repeat-containing protein 64

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001367482.1NP_001354411.1  WD repeat-containing protein 64

    Status: VALIDATED

    Source sequence(s)
    AL365366, BX248405, BX322532
    Consensus CDS
    CCDS91185.1
    UniProtKB/TrEMBL
    A0A0C4DG52
    Related
    ENSP00000402446.4, ENST00000437684.7

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    241652281..241802777
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011544087.3XP_011542389.1  WD repeat-containing protein 64 isoform X3

    Conserved Domains (3) summary
    COG2319
    Location:91538
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:468505
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:284538
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_011544091.2XP_011542393.1  WD repeat-containing protein 64 isoform X4

    Conserved Domains (3) summary
    COG2319
    Location:91538
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:468505
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:284538
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_011544092.3XP_011542394.1  WD repeat-containing protein 64 isoform X5

    Conserved Domains (3) summary
    COG2319
    Location:91538
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:468505
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:284538
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. XM_017000315.2XP_016855804.1  WD repeat-containing protein 64 isoform X1

  5. XM_011544086.4XP_011542388.1  WD repeat-containing protein 64 isoform X2

    See identical proteins and their annotated locations for XP_011542388.1

    Conserved Domains (3) summary
    COG2319
    Location:85545
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:307344
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:123377
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  6. XM_047445900.1XP_047301856.1  WD repeat-containing protein 64 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    241063753..241214784
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_144625.4: Suppressed sequence

    Description
    NM_144625.4: This RefSeq was removed because currently there is insufficient support for the transcript and protein.