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Ccr3 chemokine (C-C motif) receptor 3 [ Mus musculus (house mouse) ]

Gene ID: 12771, updated on 19-Jun-2018
Official Symbol
Ccr3provided by MGI
Official Full Name
chemokine (C-C motif) receptor 3provided by MGI
Primary source
MGI:MGI:104616
See related
Ensembl:ENSMUSG00000035448 Vega:OTTMUSG00000062932
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CKR3; Cmkbr3; CC-CKR3; Cmkbr1l2
Expression
Biased expression in spleen adult (RPKM 2.4), subcutaneous fat pad adult (RPKM 0.5) and 4 other tissues See more
See Ccr3 in Genome Data Viewer
Location:
9 F4; 9 75.05 cM
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (124017825..124031689)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (123936703..123946421)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene chemokine (C-C motif) receptor 1 Neighboring gene chemokine (C-C motif) receptor 1-like 1 Neighboring gene chemokine (C-C motif) receptor 2 Neighboring gene chemokine (C-C motif) receptor 5

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC124265, MGC124266

Gene Ontology Provided by MGI

Function Evidence Code Pubs
C-C chemokine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
C-C chemokine binding IPI
Inferred from Physical Interaction
more info
PubMed 
C-C chemokine binding ISO
Inferred from Sequence Orthology
more info
 
C-C chemokine receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
C-C chemokine receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
chemokine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chemokine receptor activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
angioblast cell migration ISO
Inferred from Sequence Orthology
more info
 
calcium-mediated signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
eosinophil chemotaxis ISO
Inferred from Sequence Orthology
more info
 
immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inflammatory response IEA
Inferred from Electronic Annotation
more info
 
mast cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytosolic calcium ion concentration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of endothelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endosome ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
probable C-C chemokine receptor type 3
Names
C-C CKR-3
CC chemokine receptor 3
CC-CKR-3
CCR-3
MIP-1 alpha RL2
MIP-1 alphaRL2
chemokine (C-C) receptor 1,-like 2
chemokine (C-C) receptor 3
macrophage inflammatory protein 1-alpha receptor-like 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009914.4NP_034044.3  probable C-C chemokine receptor type 3

    See identical proteins and their annotated locations for NP_034044.3

    Status: VALIDATED

    Source sequence(s)
    AC192862, AK041106, AK153518
    Consensus CDS
    CCDS23668.1
    UniProtKB/Swiss-Prot
    P51678
    UniProtKB/TrEMBL
    Q3U5L7
    Related
    ENSMUSP00000039107.7, OTTMUSP00000079317, ENSMUST00000039171.8, OTTMUST00000153210
    Conserved Domains (1) summary
    pfam00001
    Location:55305
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    124017825..124031689
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017313120.1XP_017168609.1  probable C-C chemokine receptor type 3 isoform X1

    UniProtKB/Swiss-Prot
    P51678
    Conserved Domains (1) summary
    pfam00001
    Location:55305
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. XM_017313119.1XP_017168608.1  probable C-C chemokine receptor type 3 isoform X1

    UniProtKB/Swiss-Prot
    P51678
    Conserved Domains (1) summary
    pfam00001
    Location:55305
    7tm_1; 7 transmembrane receptor (rhodopsin family)
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