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OR2AJ1 olfactory receptor family 2 subfamily AJ member 1 [ Homo sapiens (human) ]

Gene ID: 127608, updated on 26-Oct-2022

Summary

Official Symbol
OR2AJ1provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily AJ member 1provided by HGNC
Primary source
HGNC:HGNC:15001
See related
Ensembl:ENSG00000177275 AllianceGenome:HGNC:15001
Gene type
protein coding
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2AJ1P; OR2AJ1Q
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR2AJ1 in Genome Data Viewer
Location:
1q44
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (247924889..247935339)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (247350702..247361182)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248088191..248098641)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily W member 3 Neighboring gene olfactory receptor family 2 subfamily T member 8 Neighboring gene CDC like kinase 3 pseudogene 2 Neighboring gene olfactory receptor family 2 subfamily L member 13 Neighboring gene olfactory receptor family 2 subfamily X member 1 pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 2AJ1
Names
olfactory receptor OR1-52
olfactory receptor, family 2, subfamily AJ, member 1 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355235.2NP_001342164.2  olfactory receptor 2AJ1

    Status: INFERRED

    Source sequence(s)
    AC099571
    Consensus CDS
    CCDS91193.1
    UniProtKB/Swiss-Prot
    Q8NGZ0
    Related
    ENSP00000325078.3, ENST00000318244.4
    Conserved Domains (1) summary
    cd15421
    Location:26301
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    247924889..247935339
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    247350702..247361182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_004652.2: Suppressed sequence

    Description
    NG_004652.2: This RefSeq was removed because it is now thought that this locus is a transcribed gene.