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TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 [ Homo sapiens (human) ]

Gene ID: 127428, updated on 13-Mar-2020

Summary

Official Symbol
TCEANC2provided by HGNC
Official Full Name
transcription elongation factor A N-terminal and central domain containing 2provided by HGNC
Primary source
HGNC:HGNC:26494
See related
Ensembl:ENSG00000116205
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1orf83
Expression
Ubiquitous expression in testis (RPKM 1.1), lymph node (RPKM 0.8) and 25 other tissues See more
Orthologs

Genomic context

See TCEANC2 in Genome Data Viewer
Location:
1p32.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (54053608..54112520)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (54519274..54565416)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor class A domain containing 1 Neighboring gene transmembrane protein 59 Neighboring gene Sharpr-MPRA regulatory region 13762 Neighboring gene microRNA 4781 Neighboring gene cytochrome c oxidase subunit 7B pseudogene Neighboring gene CUB domain containing protein 2 Neighboring gene cytochrome b5 reductase like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ32112, FLJ39169

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transcription elongation factor A N-terminal and central domain-containing protein 2
Names
transcription elongation factor A (SII) N-terminal and central domain containing 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153035.3NP_694580.1  transcription elongation factor A N-terminal and central domain-containing protein 2

    See identical proteins and their annotated locations for NP_694580.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding variant.
    Source sequence(s)
    AK056674, AL161915, AL353898
    Consensus CDS
    CCDS587.1
    UniProtKB/Swiss-Prot
    Q96MN5
    Related
    ENSP00000234827.1, ENST00000234827.6
    Conserved Domains (2) summary
    cd00183
    Location:40110
    TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    pfam07500
    Location:129203
    TFIIS_M; Transcription factor S-II (TFIIS), central domain

RNA

  1. NR_130900.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate internal exon and differs at the 3' end compared to variant 1. This variant is represented as non-coding because the use of the expected ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK096488, AL161915, AL353898
    Related
    ENST00000498272.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    54053608..54112520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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