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ZNF684 zinc finger protein 684 [ Homo sapiens (human) ]

Gene ID: 127396, updated on 13-Mar-2020

Summary

Official Symbol
ZNF684provided by HGNC
Official Full Name
zinc finger protein 684provided by HGNC
Primary source
HGNC:HGNC:28418
See related
Ensembl:ENSG00000117010
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in kidney (RPKM 1.9), liver (RPKM 1.8) and 25 other tissues See more
Orthologs

Genomic context

See ZNF684 in Genome Data Viewer
Location:
1p34.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (40531637..40548167)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (40997233..41013841)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ZFP69 zinc finger protein Neighboring gene uncharacterized LOC105378672 Neighboring gene exonuclease 5 Neighboring gene Sharpr-MPRA regulatory region 98 Neighboring gene eukaryotic translation initiation factor 2 subunit gamma pseudogene Neighboring gene uncharacterized LOC105378673

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC27466

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 684
Names
hypothetical protein MGC27466

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152373.4NP_689586.3  zinc finger protein 684

    See identical proteins and their annotated locations for NP_689586.3

    Status: VALIDATED

    Source sequence(s)
    AK094072, BC111463, BG116229
    Consensus CDS
    CCDS454.1
    UniProtKB/Swiss-Prot
    Q5T5D7
    UniProtKB/TrEMBL
    B3KSP5
    Related
    ENSP00000361784.3, ENST00000372699.8
    Conserved Domains (6) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    COG5048
    Location:185345
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:301321
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:187209
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:341366
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    40531637..40548167
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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