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MYOM3 myomesin 3 [ Homo sapiens (human) ]

Gene ID: 127294, updated on 25-Jan-2022

Summary

Official Symbol
MYOM3provided by HGNC
Official Full Name
myomesin 3provided by HGNC
Primary source
HGNC:HGNC:26679
See related
Ensembl:ENSG00000142661 MIM:616832; AllianceGenome:HGNC:26679
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable actin filament binding activity and protein homodimerization activity. Predicted to be involved in muscle contraction. Predicted to be active in M band. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in heart (RPKM 41.6), kidney (RPKM 17.2) and 4 other tissues See more
Orthologs
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Genomic context

See MYOM3 in Genome Data Viewer
Location:
1p36.11
Exon count:
37
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (24056041..24112135, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (24382531..24438625, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376863 Neighboring gene ribosomal protein L36 pseudogene 5 Neighboring gene uncharacterized LOC107984931 Neighboring gene MYOM3 antisense RNA 1 Neighboring gene uncharacterized LOC105376864 Neighboring gene Sharpr-MPRA regulatory region 3135 Neighboring gene Sharpr-MPRA regulatory region 13639 Neighboring gene interleukin 22 receptor subunit alpha 1 Neighboring gene interferon lambda receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ35961, MGC71483

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in M band IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in M band ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
myomesin-3
Names
myomesin family, member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152372.4NP_689585.3  myomesin-3

    See identical proteins and their annotated locations for NP_689585.3

    Status: VALIDATED

    Source sequence(s)
    AL591178, BX647453
    Consensus CDS
    CCDS41281.1
    UniProtKB/Swiss-Prot
    Q5VTT5
    Related
    ENSP00000363557.3, ENST00000374434.4
    Conserved Domains (3) summary
    cd00063
    Location:802891
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:13341337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:13341424
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    24056041..24112135 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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