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Ckb creatine kinase, brain [ Mus musculus (house mouse) ]

Gene ID: 12709, updated on 7-Nov-2021

Summary

Official Symbol
Ckbprovided by MGI
Official Full Name
creatine kinase, brainprovided by MGI
Primary source
MGI:MGI:88407
See related
Ensembl:ENSMUSG00000001270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bck; Ck3; B-CK; Ck-3; Ckbb; CPK-B
Expression
Broad expression in cerebellum adult (RPKM 1178.4), frontal lobe adult (RPKM 855.7) and 17 other tissues See more
Orthologs
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Genomic context

See Ckb in Genome Data Viewer
Location:
12 F1; 12 61.09 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (111635789..111638772, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (111669355..111672338, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (112907566..112910549, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2810029C07 gene Neighboring gene MAP/microtubule affinity regulating kinase 3 Neighboring gene tRNA methyltransferase 61A Neighboring gene VISTA enhancer mm1606 Neighboring gene predicted gene, 51961

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables creatine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables creatine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cellular chloride ion homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in phosphocreatine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in myelin sheath HDA PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
creatine kinase B-type
Names
creatine kinase B chain
creatine phosphokinase B-type
NP_067248.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021273.4NP_067248.1  creatine kinase B-type

    See identical proteins and their annotated locations for NP_067248.1

    Status: VALIDATED

    Source sequence(s)
    AC160972, AK167034, BY654507
    Consensus CDS
    CCDS26183.1
    UniProtKB/Swiss-Prot
    Q04447
    Related
    ENSMUSP00000001304.8, ENSMUST00000001304.9
    Conserved Domains (1) summary
    cd00716
    Location:16373
    creatine_kinase_like; Phosphagen (guanidino) kinases such as creatine kinase and similar enzymes

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    111635789..111638772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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