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CCDC163 CCDC163 homolog [ Homo sapiens (human) ]

Gene ID: 126661, updated on 5-Jul-2025
Official Symbol
CCDC163provided by HGNC
Official Full Name
CCDC163 homologprovided by HGNC
Primary source
HGNC:HGNC:27003
See related
Ensembl:ENSG00000280670 AllianceGenome:HGNC:27003
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1orf231; CCDC163P
Summary
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Ubiquitous expression in thyroid (RPKM 2.5), brain (RPKM 1.4) and 25 other tissues See more
Orthologs
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See CCDC163 in Genome Data Viewer
Location:
1p34.1
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (45493866..45500073, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (45365450..45372440, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (45959538..45965745, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904849 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 967 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 968 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:45826137-45826636 Neighboring gene testis associated actin remodelling kinase 2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:45856236-45856736 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 969 Neighboring gene peptidylprolyl isomerase A pseudogene 36 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:45909108-45909337 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 829 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 970 Neighboring gene Sharpr-MPRA regulatory region 45 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:45965685-45966217 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 972 Neighboring gene metabolism of cobalamin associated C Neighboring gene ReSE screen-validated silencer GRCh37_chr1:45986750-45986912 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 973 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:45992726-45993234 Neighboring gene peroxiredoxin 1 Neighboring gene high mobility group box 1 pseudogene 48

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Markers

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
transmembrane protein CCDC163
Names
coiled-coil domain containing 163, pseudogene
coiled-coil domain-containing protein 163

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102601.3NP_001096071.1  transmembrane protein CCDC163 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL451136, BC101256, DC421969
    UniProtKB/Swiss-Prot
    A0A0D9SF12
    Related
    ENSP00000486197.1, ENST00000629482.3
  2. NM_001358406.2NP_001345335.1  transmembrane protein CCDC163 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL451136, BC113060, DC421969
    Consensus CDS
    CCDS85969.1
    UniProtKB/TrEMBL
    A0A0D9SG11, B4DV03
    Related
    ENSP00000487061.1, ENST00000626657.2
  3. NM_001358407.2NP_001345336.1  transmembrane protein CCDC163 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL451136

RNA

  1. NR_033297.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK054714, AL451136
    Related
    ENST00000625766.2
  2. NR_033298.3 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AL451136, BC101257
    Related
    ENST00000626177.2
  3. NR_152411.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL451136
  4. NR_152412.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL451136
  5. NR_152413.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL451136
  6. NR_152414.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL451136, BC113061, DC421969

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    45493866..45500073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024453044.2XP_024308812.1  transmembrane protein CCDC163 isoform X1

  2. XM_024453045.2XP_024308813.1  transmembrane protein CCDC163 isoform X2

  3. XM_047444595.1XP_047300551.1  transmembrane protein CCDC163 isoform X3

  4. XM_047444605.1XP_047300561.1  transmembrane protein CCDC163 isoform X4

    UniProtKB/TrEMBL
    B4DV03
    Related
    ENST00000628397.2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    45365450..45372440 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054334227.1XP_054190202.1  transmembrane protein CCDC163 isoform X1

  2. XM_054334228.1XP_054190203.1  transmembrane protein CCDC163 isoform X2

  3. XM_054334229.1XP_054190204.1  transmembrane protein CCDC163 isoform X3

  4. XM_054334230.1XP_054190205.1  transmembrane protein CCDC163 isoform X4

    UniProtKB/TrEMBL
    B4DV03