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WTIP WT1 interacting protein [ Homo sapiens (human) ]

Gene ID: 126374, updated on 23-Nov-2021

Summary

Official Symbol
WTIPprovided by HGNC
Official Full Name
WT1 interacting proteinprovided by HGNC
Primary source
HGNC:HGNC:20964
See related
Ensembl:ENSG00000142279 MIM:614790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in fat (RPKM 6.5), ovary (RPKM 5.4) and 23 other tissues See more
Orthologs
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Genomic context

See WTIP in Genome Data Viewer
Location:
19q13.11
Exon count:
10
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (34481758..34512304)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (34972663..35003209)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene programmed cell death 2 like Neighboring gene RNA, 7SL, cytoplasmic 154, pseudogene Neighboring gene ubiquitin like modifier activating enzyme 2 Neighboring gene ribosomal protein S26 pseudogene 55 Neighboring gene uncharacterized LOC105372374 Neighboring gene zinc finger protein 807, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in P-body IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Wilms tumor protein 1-interacting protein
Names
Wilms tumor 1 interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080436.2NP_001073905.1  Wilms tumor protein 1-interacting protein

    See identical proteins and their annotated locations for NP_001073905.1

    Status: VALIDATED

    Source sequence(s)
    AC008747
    Consensus CDS
    CCDS59375.1
    UniProtKB/Swiss-Prot
    A6NIX2
    Related
    ENSP00000466953.2, ENST00000590071.7
    Conserved Domains (3) summary
    cd09352
    Location:225278
    LIM1_Ajuba_like; The first LIM domain of Ajuba-like proteins
    cd09355
    Location:290342
    LIM2_Ajuba_like; The second LIM domain of Ajuba-like proteins
    cd09438
    Location:350411
    LIM3_Ajuba_like; The third LIM domain of Ajuba-like proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    34481758..34512304
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526452.3XP_011524754.1  Wilms tumor protein 1-interacting protein isoform X1

    Conserved Domains (3) summary
    cd09352
    Location:225278
    LIM1_Ajuba_like; The first LIM domain of Ajuba-like proteins
    cd09355
    Location:290342
    LIM2_Ajuba_like; The second LIM domain of Ajuba-like proteins
    cl02475
    Location:350404
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  2. XM_006723014.4XP_006723077.1  Wilms tumor protein 1-interacting protein isoform X2

    Conserved Domains (3) summary
    cd09352
    Location:225278
    LIM1_Ajuba_like; The first LIM domain of Ajuba-like proteins
    cd09355
    Location:290342
    LIM2_Ajuba_like; The second LIM domain of Ajuba-like proteins
    cl02475
    Location:350384
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  3. XM_011526453.3XP_011524755.1  Wilms tumor protein 1-interacting protein isoform X3

    Conserved Domains (2) summary
    cd09355
    Location:49101
    LIM2_Ajuba_like; The second LIM domain of Ajuba-like proteins
    cl02475
    Location:137
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
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